Have you ever wondered what environmental toxins you are exposed to on a daily basis, and how it might affect your health? The STRIVE study is looking for volunteers who would like to provide blood, urine, and/or saliva, as well as home samples such as soil, dust, and/or water. In this study, we want to learn more about the environmental factors that contribute to advanced liver disease and liver cancer. We are looking for healthy volunteers and people with liver cirrhosis who live in either North Carolina or Georgia to take part.

Do you have a child between 12-14 years of age who is healthy but has some symptoms of anxiety or unexplained nervousness? You may be able to take part in a study with your child to better understand how anxiety develops across adolescence in brain and stress responses. Compensation provided.

Think you have good reaction time? Would you like to get involved in research? You may be able to participate in a research study for upper extremity reaction time.

Have you ever been diagnosed with metastatic triple negative breast cancer and received 2 or less lines of chemotherapy for your metastatic disease? If so you may be eligible for a trial to evaluate different treatment combination with avelumab for your metastatic breast cancer.

Participants are asked to come into the lab for a 1.5-hour session. During this session they will complete questionnaires and tasks. Questionnaires will ask about physical and mental health, life experiences, emotions, and cognitive associations. Tasks are designed to measure participants' sensitivity to heartbeat and stomach sensations, as well as socioemotional functioning.

Metabolism is the process your body uses to make energy. The main purpose of this study is to observe the impact of metabolic processes on cognition and behavior.

Fuel for Thought: How do sugar and fat affect each other in the brain? Do you ever wonder what happens in your brain when you eat dessert? And why sugary and fatty foods are so appealing? If so, you may eligible to participate in a research study to understand the impact of sugar and fat on the brain!

Did you know that over 250 million persons are affected by Osteoarthritis? It is the leading cause of disability among adults and has no cure. Prevention of OA is preferable to treatment and females are affected at nearly twice the rate as males. If you are a female, at least 50 years of age, overweight, with no or occasional knee pain, you may be able to participate in a research study to find out if a diet and exercise program or a health education program prevent knee OA.

If you are healthy and between the ages of 18-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Are you scheduled for weight loss surgery within the next 12 months? You may be able to take part in a research study to help us learn more about your metabolic hormones, eating behaviors, stress, and weight loss before and after your surgery.