Did you know that over 250 million persons are affected by Osteoarthritis? It is the leading cause of disability among adults and has no cure. Prevention of OA is preferable to treatment and females are affected at nearly twice the rate as males. If you are a female, at least 50 years of age, overweight, with no or occasional knee pain, you may be able to participate in a research study to find out if a diet and exercise program or a health education program prevent knee OA.

If you are healthy and between the ages of 18-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Are you scheduled for weight loss surgery within the next 12 months? You may be able to take part in a research study to help us learn more about your metabolic hormones, eating behaviors, stress, and weight loss before and after your surgery.

Nutrition is not one-size-fits-all. Nutrition, or the foods we eat, can help prevent and fight conditions such as high blood pressure, diabetes, stroke, and more. However, we all live in different environments, we come from different cultures, and each of us is starting from a different place with our health. Additionally, everyone breaks down food differently. Join the Nutrition for Precision Health research study to help researchers learn how our genes, cultural backgrounds, and environments affect our bodies' responses to food. Compensation provided.

During puberty, adolescents grow and change a lot which may make life seem more stressful and emotional. Male and female adolescents experience the changes associated with puberty differently, possibly because of different responses to changes in hormones, including testosterone and estrogen. We are interested in learning more about the role of these hormones in regulating emotional processing and mood symptoms, and whether a mobile training program can help improve mood during the pubertal transition. Participation is 8 weeks with two monthly follow-up surveys. Compensation provided.

We're all different. But when we visit the doctor, our treatments are often the same. We think one day health care should be tailored for you. This is called precision medicine. And research can help us get there. Taking part in the All of Us Research Program involves sharing information about your health, habits, and what it's like where you live. If you are 18 or older and live in the United States, you may be able to take part!

In the Carolina Blue Project, we want to learn more about work-related stress, eating behaviors, and cardiovascular disease risk factors among law enforcement officers. If you work as a law enforcement officer in any North Carolina or nearby states law enforcement department, you may be able to take part in this study. We do not collect any personally identifiable information. Officers who participate in the project and complete the two required steps will receive a $100 Amazon gift card.

Are you interested in how changes in shoes and footwear can be used to make improvements to day-to-day life? You may be able to participate in a research study to quantify the biomechanical effects of different footwear on walking. Compensation provided.

Does your child have hearing loss in one ear, or single-sided deafness? If they are under the age of 3, they may be able to receive a cochlear implant as part of a research study to find out if early implantation helps children with single-sided deafness. If they are five, they may be able to help us study differences between children who receive a cochlear implant when they are little, children who do not receive a cochlear implant, and those with typical hearing.

Interested in participating in future research studies? Whether you have had a previous ACL injury or not, you may be able to take part in several research study opportunities. This registry simply collects your contact information and then we will reach out if any study opportunities are available.