Are you someone living with Parkinson's disease? If so, you are aware that in addition to symptoms affecting movement, people with Parkinson's disease also experience non-motor symptoms such as problems with mood and motivation which can be difficult to treat. If you have been living with Parkinson's disease for at least 5 years and take medication for Parkinson's disease, you may be eligible to participate in a research study aimed at treating low motivation with a form of non-invasive brain stimulation called transcranial magnetic stimulation (TMS).

The purpose of this study is to identify and genomically-characterize individuals with genetically unexplained neurodevelopmental disorders, such as epilepsy. The overarching goal is to provide patients with improved information about the underlying genetic basis of their disorder and illuminate novel genetically-defined treatment approaches in the future.

Do you have probable Dementia with Lewy Bodies (DLB), Mild Cognitive Impairment with "high likelihood" DLB, or Parkinson's Disease Dementia (PDD)? You may be able to participate in an observational study to track your disease progression and promote future research.

The purpose of the study is to establish a Clinical Cohort (group) of research participants to examine normal cognition, mild cognitive impairment and Alzheimer's disease and related disorders (ADRD) as people get older. We will be measuring changes in your memory and the way you process information as you age. As part of the study, you will be asked to participate in yearly evaluations of your memory and health. You will have brain imagining done by Magnetic Resonance Imaging (MRI), a lumbar puncture and blood will be drawn at some visits. Also, as part of this research you must designate a "project partner." This should be someone who is familiar with your health and will be able to provide information about your health and wellbeing as appropriate.

The purpose of the HEALEY ALS Platform Trial is to develop and administer various clinical trials under different regimens with ALS to provide multiple treatment options for patients with ALS.

The purpose of this study is to test the safety and effectiveness of DNL343.

This study will gather information about patients who are taking new medicines for Alzheimer's disease. We'll keep an eye on how these patients are doing in the long run, tracking things like how they're responding to treatment, what their overall health outcomes are like, and how safe these new treatments really are when used in the real world. The goal of this study is to get a better understanding of how these therapies actually work for a diverse group of people, not just the people who usually participate in clinical trials.

The purpose of this study is to test the safety and effectiveness of ABBV-CLS-7262 on ALS disease progression.