Have you been listed for kidney transplant at UNC? If so, you may be able to take part in a research study to help us learn how the process of waiting for a kidney transplant impacts you.

People with kidney disease that have the APOL1 risk variant are at a greater risk for developing protein in their urine and chronic kidney disease. This research study is being done to determine if the investigational drug, VX-147 can slow or stop the worsening of kidney function as well as target the underlying cause of kidney disease.

We still have a lot to learn about why people develop glomerular disease and what the best medicines are to treat these diseases. Diabetes is a common, chronic illness and many people with glomerular disease also have diabetes. Currently, there is no information telling us the best ways to treat patients with both diabetes and glomerular disease, or how to counsel them about prognosis and risks for complications. This substudy of the Cure Glomerulopathy Network brings together information and laboratory specimens from patients with diabetes and glomerular disease to speed up and improve health research for their care.

The CureGN Network acts as a "library" of data for investigators across the world to use to help us ask the following questions: 1) What is the disease?; 2) Why did it happen to me?; 3) Can it be passed down to my family members?; 4) What treatments work the best with the least side effects?

If you've had a kidney biopsy and learned you have a specific kidney condition, you might be eligible to join a three-year study. This study looks at how two medicines, when used together, might help treat your condition.

If you have been treated with ANCA vasculitis and you are now in remission, you may be able to participate in a study to test if a specific blood test can help your doctor decide if you need maintenance therapy.

We are looking for patients with kidney disease and healthy controls (no kidney disease) to provide blood samples, fill out surveys, and provide health related information to help investigators learn more about how to better diagnose and treat kidney disease. The information you provide will go into a "library" of data for doctors and researchers across the world to use for research projects. If you are a kidney patient, we are able to use your information to find out if you are eligible for treatment studies/other studies in the future.