Are you an adult who has just found out you have IDH-Wildtype Glioblastoma? If so, you could join a study to see if a new experimental pill called ropidoxuridine can help make treatment for this type of brain cancer better when used with radiation.
Have you been diagnosed with High-risk Biochemical Recurrence (BCR) of Nonmetastatic Castration-sensitive Prostate Cancer (nmCSPC)? If so, you may be able to take part in a research study evaluating the safety and tolerability of the study drug in adults with High-risk Biochemical Recurrence (BCR) of Nonmetastatic Castratio-sensitive Prostate Cancer (nmCSPC).
Do you have early-stage endometrial cancer? If so, you may be able to take part in a research study looking to find out if there are types of early-stage endometrial cancer that require less treatment than the usual approac
Do you struggle with ways to feel more relaxed or calm when you are stressed? Do you identify as African American, Black, Hispanic, and/or Latino (a/e/x)? If so, you may be able to take part in a study to see whether a home-based training program can improve emotional well-being and heart health. Compensation provided.
Do you have advanced melanoma that has progressed on treatment? Do you have a tumor longer than 1cm in length? If so, you might be able to take part in a study that compares a study treatment (Vusolimogene Oderparepvec and Nivolumab) with your physician's choice of standard of care treatment. Compensation provided.
Have you been diagnosed with hormone receptor (HR+) and human epidermal growth factor receptor 2 (HER2)-negative recurrent or metastatic breast cancer? If so, you may be eligible for a clinical trial investigating the combination of endocrine therapy with alisertib.
Have you been diagnosed with cancer. If so, you may be able to take part in a research study looking to improve cancer care for patients whose treatment outcomes have led to challenges in their quality of life.
Does hypertonic saline improve mucus clearance in bronchiectasis? The purpose of this research study is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lungs in people with bronchiectasis. We will compare mucociliary clearance (MCC: a measurement of the rate at which a person's lungs can clear inhaled particles) at baseline, after a single dose of HS, and after two weeks of treatment with HS twice a day. We will also assess response to HS with other outcomes (spirometry, multiple breath washout [MBW], changes in sputum [coughed up mucus or phlegm], and survey responses). Compensation provided. No blood draws required.
Are you a patient with advanced basal-like pancreatic adenocarcinoma? If so this could the a Trial for you to as this is a Phase I/II trial is to evaluate the safety, efficacy and tolerability of low-dose EGFR inhibitors in combination with bi-weekly gemcitabine/nab-paclitaxel (GnP) in subjects with basal tumors
Is your child being hospitalized at UNC Youth Behavioral Health for suicidal thoughts or behaviors? If so, you may be eligible to participate in a research study to identify the risk factors associated with recurrence of suicidal thoughts after psychiatric hospitalization. Both you and your child must participate to be eligible for the research study. Compensation provided.