Are you suspected of having or have been diagnosed with ovarian cancer? if so, you may be able to participate in a research study looking at creating personalized stem cells from the skin of ovarian cancer patients to see if these stem cells can attack cancer cells. This work may be able to help us find more treatment options for ovarian cancer patients in the future.

Have you been diagnosed with metastatic brain cancer (tumor)? If so, you may be able to take part in a research study looking at the safety of giving radiation therapy through a device called GammaTiles™ to patients with newly diagnosed metastatic brain tumors planned for surgical resection.

Have you been diagnosed with Leukemia? You may be able to take part in a research study to find out if a new study drug can help put your blood cancer into remission.

Are you a patient with locally advanced or metastatic squamous cell carcinoma? If so, you may be eligible to participate in a clinical research study involving an investigational drug, NBTXR3.

Can we increase the clinical complete response rate (tumor disappears by exam, endoscopy, and imaging) by adding a 3rd drug (irinotecan) to the standard regimen of FOLFOX or CAPOX given following long-course chemoradiation for patients with locally advanced rectal cancer? We are doing this study because we want to find out if this approach is better or worse than the usual approach for your rectal cancer. The usual approach is defined as care most people get for locally advanced rectal cancer.

Do you have newly-diagnosed multiple myeloma? If so, you may be able to participate in a research study looking at the safety, efficacy, and tolerability of giving isatuximab in combination with lenalidomide and dexamethasone at lower doses.

Have you been diagnosed with multiple myeloma that has not responded to treatment or has come back after treatment? If so, you may be able to take part in a research study looking at the safety and efficacy of giving a new drug called ABBV-383 to patients with relapsed/refractory multiple myeloma.

Do you have ovarian or peritoneal cancer? if so, you may be able to participate in a research study comparing the treatment of carboplatin/paclitaxel and letrozole hormonal therapy to letrozole alone to see if the treatment can shrink or stabilize your cancer.

Have you been diagnosed with uterine pre-cancer (endometrial intraepithelial neoplasia, EIN) ? if so, you may be able to participate in a research study to see if giving metformin and megestrol acetate together may decrease the growth of endometrial intraepithelial neoplasia in the uterus better than megestrol alone.

We're all different. But when we visit the doctor, our treatments are often the same. We think one day health care should be tailored for you. This is called precision medicine. And research can help us get there. Taking part in the All of Us Research Program involves sharing information about your health, habits, and what it's like where you live. If you are 18 or older and live in the United States, you may be able to take part!