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UNC-Chapel Hill Department of Neurology

9 studies match your search
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ARGX-117-2302- Phase 3, Randomized, Double-Blind study to evaluate effectiveness and safety of empasiprubart versus IVIg in patients with multifocal motor neuropathy

This study aims to evaluate the effectand safety of empasiprubart compared with intravenous immunoglobulin (IVIg) treatment in adults with multifocal motor neuropathy (MMN). This study will also check how empasiprubart affects the body, how it is absorbed and removed from the body, and how the immune system reacts to empasiprubart.

Age & Gender
  • 18 years ~ 99 years
  • Male, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Open

A Randomized, Double-Blinded, Placebo-Controlled, Phase 3, Study in Adult Participants With Ocular Myasthenia Gravi

The aim of this study is to measure the efficacy (how well it works) and safety of efgartigimod compared with placebo (inactive substance) in participants with ocular myasthenia gravis (oMG). The study will also measure the long-term efficacy, safety, and tolerability of efgartigimod.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Not currently enrolling

Parkinson's Disease Treatment study

In this study, we are trying to find out how safe and helpful a new drug is when it is put directly into the brain during surgery. This drug is used to help with the movement problems caused by Parkinson's disease.

Age & Gender
  • 45 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Visit Location
Open

The ADD-Me Roster: a registry for those interested in brain health or Alzheimer's research

Do you have problems with your thinking or memory? Or a parent or sibling with dementia? If so, we'd like you to join this registry about the brain and Alzheimer's disease. In return for providing us with a little bit of your health history and background, we will connect you with researchers doing studies you can join, without obligation. Many studies pay a stipend and some offer a possible treatment.

Age & Gender
  • 45 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Brain, Head, Nervous System
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
Not currently enrolling

Genetic Determinants of Neurological and Developmental Disorders

The purpose of this study is to identify and genomically-characterize individuals with genetically unexplained neurodevelopmental disorders, such as epilepsy. The overarching goal is to provide patients with improved information about the underlying genetic basis of their disorder and illuminate novel genetically-defined treatment approaches in the future.

Age & Gender
  • 0 days ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Developmental
  • Genetics and Genetic Disorders
  • Rare Diseases
Open

DLB Consortium

Do you have probable Dementia with Lewy Bodies (DLB), Mild Cognitive Impairment with "high likelihood" DLB, or Parkinson's Disease Dementia (PDD)? You may be able to participate in an observational study to track your disease progression and promote future research.

Age & Gender
  • 40 years ~ 90 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Mental and Emotional Health
By physician referral or invitation only

Anticoagulation in Intracerebral Hemorrhage Survivors for Stroke Prevention and Recovery (ASPIRE)

The ASPIRE trial aims to study anticoagulant medications in patients who have had an intracerebral hemorrhage (bleeding in the brain) who also have atrial fibrillation (irregular heartbeats). Participants who agree to study participation will receive either Aspirin or Apixaban and followed for 12-36 months to see if they have any other strokes, and follow their general recovery after stroke.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Heart and Circulation
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Alzheimer's Network for Treatment and Diagnostics

This study will gather information about patients who are taking new medicines for Alzheimer's disease. We'll keep an eye on how these patients are doing in the long run, tracking things like how they're responding to treatment, what their overall health outcomes are like, and how safe these new treatments really are when used in the real world. The goal of this study is to get a better understanding of how these therapies actually work for a diverse group of people, not just the people who usually participate in clinical trials.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Registry of Patients with AQP4+ NMOSD Treated with Alexion C5 Inhibitor Therapies

This clinical trial aims to understand how well ALXN-C5IT works over a long time. We want to see if it can prevent relapses and help with disability, walking, and vision. We also want to know how patients feel about their health while using ALXN-C5IT.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Visit Location
100% Remote (online, phone, text)
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