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UNC-Chapel Hill Lineberger Comprehensive Cancer Center

242 studies match your search
Coming Soon

Relapsed and Refractory CLL, SLL, and Select Low-grade Lymphomas Treatment Study

In this study, we are looking at a medicine called ZE50-0134 that might help treat people with relapsed and refractory CLL, SLL, or certain low-grade lymphomas. We want to see if taking different amounts of this medicine in capsule form is safe for patients.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Lymphoma)
Coming Soon

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

To investigate the feasibility of the referral and engagement process in fatigue mitigation intervention for cancer-related fatigue among adults with CLL or other forms of indolent lymphoma.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lymphoma)
Coming Soon

APVO436-5201: APVO436 Phase 1b/2 Study in Patients with Newly Diagnosed acute myeloid leukemia (AML).

We are looking for a dose of the APVO436 in combination with venetoclax and azacitidine that can be administered safely to participants who have been diagnosed with AML.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia)
Open

Understanding How Couples Dealing With Prostate Cancer Handle Meals and Food Choices

Are you and your partner dealing with prostate cancer? Healthy eating is an important part of managing prostate cancer. If you or your partner has been diagnosed with prostate cancer, you are invited to join this study. We will talk with both of you about how you discuss healthy eating, prepare meals, and eat together.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Behavior
  • Eating, Nutrition, and Metabolism
  • Men's Health
  • and 2 more
Visit Location
100% Remote (online, phone, text)
Coming Soon

P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma (MM)

The purpose of this study is to find out if an investigational treatment called P-BCMA-ALLO1 is safe and will help treat people with Multiple Myeloma. The study is also being done to determine what dose is safe and effective to treat Multiple Myeloma.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Multiple Myeloma)
Open

Comparison of Two Anticancer Drug Combinations in Colorectal Cancer

Do you have metastatic colorectal cancer? Does your cancer lack certain mutations? If so, you might be eligible to take part in a trial to look at the effects of an investigational anticancer drug given with normal therapy.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Colorectal)
Coming Soon

Study of GIVinostat and Hydroxyurea for High-Risk Polycythemia Vera

The purpose of this study is to see if an investigational drug, GIVinostat, can help treat adults with a blood condition called Polycythemia Vera.

Age & Gender
  • 18 years ~ 99 years
  • Male, Gender Inclusive
Study Interest
  • Blood Conditions
Coming Soon

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

In this study, we will look at two medicines called venetoclax and obinutuzumab for patients whose chronic lymphocytic leukemia has come back. We will also check if this treatment is safe for them.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Lymphoma)
Open

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Do you have thyroid cancer? If so, you may be eligible to participate in a research study to see which targeted therapy will work better to prolong the time until your tumor grows or spreads, after initial treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Thyroid and Other Gland/Endocrine)
Open

Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy with Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)

Have you been diagnosed with early-stage breast cancer or ductal carcinoma in situ (DCIS) and have undergone breast conserving surgery (lumpectomy). If so this may be the research for you!! You may be able to take part in a research study to evaluate the effects of the tumor bed boost when given at the same time (called a simultaneous integrated boost, SIB) with the WBI, as opposed to after the WBI.

Age & Gender
  • 50 years ~ 99 years
  • Female
Study Interest
  • Cancer (Breast)
  • Women's Health
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