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UNC-Chapel Hill Lineberger Comprehensive Cancer Center

242 studies match your search
Not currently enrolling

Radiation-Induced Xerostomia Long-Term Follow-Up Study

In this study, we want to asses the long-term safety of using a virus to deliver a gene, AAV2-hAQP1, and how effective this gene is at treating dry mouth in people who have received radiation therapy for head and neck cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)

Dara-RVd Induction for newly diagnosed multiple myeloma with autologous stem cell transplantation

In this study, we want to see what happens when one of the drugs in a 4-drug combination called Dara-RVd is given once a week instead of twice a week. We will look at how this timing change affects the outcome of multiple myeloma with autologous stem cell transplantation. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Multiple Myeloma)
Open

Study for Patients with Non-small Cell Lung Cancer

Have you been diagnosed with Stage III non-small cell lung cancer? Is your cancer advanced and not able to to removed? If so, you might be able to participate in a study that looks at a study drug to see if it can help the radiation treatment work better against your cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
Open

PRevention Of Frailty with Fisetin (PROFFi) in Breast Cancer Survivors

Are you a breast cancer survivor? if soy you may be eligible to participate in this research study that is looking at the effectiveness of fisetin and/or exercise on physical function assessed using a 6 minute walking distance in chemotherapy-treated postmenopausal breast cancer survivors

Age & Gender
  • 18 years ~ 70 years
  • Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Not currently enrolling

Metastatic Non-small Cell Lung Cancer Treatment

In this study, we want to see how patients with metastatic non-small cell lung cancer do with two treatments: ivonescimab and chemotherapy. We are comparing these treatments to find out which one helps patients more.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Open

EFFICACY AND SAFETY OF DIVARASIB VERSUS SOTORASIB OR ADAGRASIB IN PATIENTS WITH NON-SMALL CELL LUNG CANCER

Do you have non small cell lung cancer? Are you currently not on any other treatments for your cancer? If you answered yes, you may be able to take part in a lung cancer medication study.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Open

Advanced Cancer Decisions Study

Do you have an advanced cancer? Are you 60+ years old? If so, you may be able to take part in a study to understand how patients and doctors communicate when choosing treatments. Compensation provided.

Age & Gender
  • 60 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder, Brain and Other Nervous System, Breast, and 15 more)
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Effects of pre-compression on ultrasound elastography measurements in healthy breast tissue

Ultrasound imaging can be used to non-invasively estimate the stiffness and viscosity of tissues within the body in order to diagnose disease. Many tissues, such as muscle or breast, are anisotropic and display differing stiffness or viscosity based on the imaging angle. We aim to optimize an imaging sequence to measure stiffness, viscosity, and the degree of anisotropy (DoA) of these parameters in healthy human breast. This will enable future studies on the diagnostic value of ultrasound elastography for detecting breast pathologies.

Age & Gender
  • 30 years ~ 90 years
  • Female
Study Interest
  • Cancer (Breast)
  • Healthy Volunteer or General Population
  • Women's Health
Open

Phase 1/2 Study of BDTX-1535 in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR

Do you have a cancer that is advanced or metastatic? Has your cancer progressed on other standard of care therapies? If you answered yes, then this research study may be for you. Study drug will be provided

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Open

Physical Activity Treatment Study

Do you identify as Black or African-American? Have you been diagnosed with colon cancer, rectal cancer, or colorectal cancer? If so, you may be able to take part in a study to see if an exercise program can help with cancer side effects and overall quality of life. Compensation provided,

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Colorectal)
  • Wellness and Lifestyle
  • Movement
Visit Location
100% Remote (online, phone, text)
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