By joining, you'll share important health information in a secure research registry to help scientists: -Understand how the immune system reacts to food -Improve diagnosis and treatment -Develop prevention strategies and new therapies

Do you have cutaneous sarcoidosis? Would you be interested in hearing more about a clinical study on cutaneous sarcoidosis? If so, you may be able to participate in a research study to find out how effective and safe the study medication Brepocitinib is in patient with cutaneous sarcoidosis.

Are you 21+ and regularly drink alcohol? You may be eligible for a study to help us learn what people think about alcohol. Participants who complete the study can earn up to $275 in virtual gift cards.

The main purpose of the study is to determine whether the experimental study drug, AI-081, is safe and well tolerated, and whether it is effective in treating advanced cancer that cannot be removed by surgery or has spread to a different part of the body (metastasis).

Are you interested in an eye-tracking study? Participate in our study! We are giving $15/hour or 1 SONA credit (plus 0.5 extra travel credit). This study is approximately one hour long. This is a research study and not a clinical treatment study. We are researching where people look while they listen to stories and view pictures about such stories. You are eligible to participate if you are 18 years or older, a native speaker of American English, with vision good enough to see and read a computer screen, and able to attend an in-person visit in the Arnold Lab, Room 371, Davie Hall at UNC. You must not have participated in other Arnold lab studies before. If you wear glasses and use lenses as well, we request that you wear lenses for the ease of participation. Also, we request that you not wear any eye makeup during participation.

This trial will follow approximately 200 patients with HER2-low (IHC<2+) MBC who are starting T-DXd. The study will test a newly developed test to measure HER2 protein on tumor cells using an antibody that 'lights up' when attached to HER2. The 'light' is called fluorescence. Cells with HER2 light up when viewed under a microscope with a special light. The fluorescence strength matches with the amount of HER2 protein on the breast cancer cell. We propose to prove this test works in patients with MBC that is HER2 low (IHC<2+) and who are beginning treatment with T-DXd. Each patient in this study will have their tumor tested using this new fluorescence test (Quantitative Immunofluorescence, or QIF). Patients will be followed for response to T-DXd. We will compare the QIF score with IHC score as they relate to patients who benefit from T-DXd. We propose that QIF will more reliably tell

Are you planning on having an IUD placed? If you are already planning to get an IUD, this study gives the chance to receive extra pain medication during insertion. Everyone will receive standard pain medication, and 2/3 of volunteers will receive extra. We are looking to see if giving ketorolac pills 1-hour vs 2-hours before an IUD decreases pain levels. We would need 3 hours of in-person clinic time from volunteers. Compensation provided.

Do you have depression and are currently experiencing depression symptoms? We are conducting a treatment trial to see whether non-invasive brain stimulation that matches your brain waves can improve depression symptoms. This is a randomized controlled trial where participants will be randomly assigned to receive active or placebo (fake) stimulation. Compensation is provided.

The purpose of this study is to compare the usual treatment with hormonal therapy medications to treatment with low-dose tamoxifen. This study will help the study doctors find out if this different approach is the same as the usual approach. To decide if it is better, the study doctors will be looking to see if low-dose tamoxifen has the same chance of preventing breast cancer from returning compared to the usual hormonal therapy medications with less side effects

Are you an adult with an intellectual disability (ID/D) age 18 to 30 years? Would you and your adult care partner like to participate in a one-hour zoom interview together to answer questions that can help researchers learn about school and community experiences and technology use that helps people with ID/D transition to adulthood? Digitial gift card compensation provided to both participants.