In this study we want to find out how much alcohol people drink every day affects if someone gets sick more easily. We want to see if this is different in people who drink different amounts or those who have a problem with alcohol.

Do you struggle with ways to feel more relaxed or calm when you are stressed? Do you identify as African American, Black, Hispanic, and/or Latino (a/e/x)? If so, you may be able to take part in a study to see whether a home-based training program can improve emotional well-being and heart health. Compensation provided.

The purpose of this study is to understand how much people know about skin cancer and how they protect their skin. We are looking at people's knowledge about different types of skin cancer and their behaviors to prevent it. We want to see if there are common habits or barriers that affect how people take care of their skin. By learning more about these things, we hope to improve ways to promote skin health and prevent skin cancer.

Do you have advanced melanoma that has progressed on treatment? Do you have a tumor longer than 1cm in length? If so, you might be able to take part in a study that compares a study treatment (Vusolimogene Oderparepvec and Nivolumab) with your physician's choice of standard of care treatment. Compensation provided.

Have you been diagnosed with hormone receptor (HR+) and human epidermal growth factor receptor 2 (HER2)-negative recurrent or metastatic breast cancer? If so, you may be eligible for a clinical trial investigating the combination of endocrine therapy with alisertib.

Have you been diagnosed with cancer. If so, you may be able to take part in a research study looking to improve cancer care for patients whose treatment outcomes have led to challenges in their quality of life.

Does hypertonic saline improve mucus clearance in bronchiectasis? The purpose of this research study is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lungs in people with bronchiectasis. We will compare mucociliary clearance (MCC: a measurement of the rate at which a person's lungs can clear inhaled particles) at baseline, after a single dose of HS, and after two weeks of treatment with HS twice a day. We will also assess response to HS with other outcomes (spirometry, multiple breath washout [MBW], changes in sputum [coughed up mucus or phlegm], and survey responses). Compensation provided. No blood draws required.

The purpose of this research study is to gain insight into how people interact with some of Spotify's features including Discover Weeklyl, DJ, and Daylist. We want to learn more about the factors that influence how users discover new music when using these features.

The purpose of this research study is to investigate how human interpret some predictive learned by AI systems when detecting deceptive hotel reviews and how AI explanations can shape human understanding. For instance, the AI system learns that words like "floor" and "bathroom" are highly predictive of genuine reviews and words like "husband" and "luxury" are highly predictive of deceptive reviews. While the AI system highlights these words by learning from the data, the association between these words and the outcome are not easy to comprehend for humans. Thus, our goal of this research is to investigate how participants interact with machine-generated explanations that are unintuitive, and how participants make use of our developed visualizations and tools to make sense of these unintuitive features.

The purpose of this study is to test a brain stimulation device in Adults with Depression. We aim to make sure the device functions as designed and appropriately stores and transmits data.