Study the effects of a new drug LY3540378 in patients with heart failure

We are looking at nasal markers in patients undergoing treatment of allergies to see if these markers can help predict who will respond successfully to treatment.

The purpose of this study is to better understand the experiences of individuals who have been diagnosed with certain bleeding disorders.

Compare the use of ACL reconstruction and physical therapy in Black and White people and people with different socioeconomic status after ACL injury. Black people and people with lower socioeconomic status are at higher risk of long-term disability related to arthritis that is common after ACL injury. The above treatments may reduce long-term disability, but use of these treatments may be different across racial and socioeconomic groups. The project will also look at factors related to treatment use in Black people with ACL injury. Identifying these factors will help us figure out how to improve treatment use in Black people, who are often underrepresented in clinical research. *This study is a collaboration with the UNC Sports Medicine Institute*

This study will evaluate the safety and effectiveness of a new intravenous (IV) medication (LT3001) for adult patients who have had a stroke. This new medication is designed to restore blood flow to the area of the brain affected, and reduce inflammation in the brain. Patients who agree to be in this study will receive 6 doses of the IV study drug while in the hospital. Patients will have extra labs drawn, head imaging studies and will be followed by the study team for 90 days after their hospital admission.

The purpose of this study is to understand how people think about different aspects of time (past, present, and future) and its association with their well-being in romantic relationships.

Cancer affects the entire family - including children. FACT, which stands for "Families Addressing Cancer Together," is a new online tool that generates custom guidance for discussing cancer with children, tailored for your unique family and goals.

We are conducting this study to better understand the relationship between access to care, financial stress and health related quality of life among cancer patients in NC who live in rural areas. We will be interviewing 30 rural cancer patients to learn about their cancer experience and we will be reviewing previously completed surveys about their distress and coping behaviors.

The purpose of this project is to evaluate the following: 1. Are registered pharmacists in North Carolina aware of their authority as immunizing pharmacists to dispense, deliver or administer self-administered oral or transdermal contraceptives to a patient; 2. Of pharmacists that have registered for and completed the NC hormonal contraceptive training, how many have implemented this service for patients; and 3. Complete semi-structured interviews of pharmacists that have or have not implemented the service to understand their motivations and perceptions of and ability to expand access to hormonal contraception and/or address barriers to implementation.

To increase access to Pre-Exposure Prophylaxis (PrEP) across North Carolina. HIV Pre-Exposure Prophylaxis (PrEP) medication has been proven to be effective at preventing HIV infection when taken as prescribed. Even though PrEP has been shown to be effective, not all health care settings currently offer PrEP to their patients. Part of the reason for this is that there are not enough health care providers who prescribe PrEP, and, some people have difficulty getting the cost of PrEP and PrEP care covered. The purpose of this study is to test new ways to increase access to PrEP for people in North Carolina. The intervention will test whether providing access to resources related to PrEP care at health department sexually transmitted infection (STI) clinics will increase the number of people who start using PrEP.