In this study we want to find out how much alcohol people drink every day affects if someone gets sick more easily. We want to see if this is different in people who drink different amounts or those who have a problem with alcohol.

Do you want to try out a smart ring? Do you want to get access to smartphone application which provides insightful information about your overall health, sleep, and activity? If you are between 40-59 years old, you may be able to participate in a research study assessing the feasibility and acceptability of Oura Rings.

The purpose of this study is to understand how much people know about skin cancer and how they protect their skin. We are looking at people's knowledge about different types of skin cancer and their behaviors to prevent it. We want to see if there are common habits or barriers that affect how people take care of their skin. By learning more about these things, we hope to improve ways to promote skin health and prevent skin cancer.

Do you struggle with ways to feel more relaxed or calm when you are stressed? Do you identify as African American, Black, Hispanic, and/or Latino (a/e/x)? If so, you may be able to take part in a study to see whether a home-based training program can improve emotional well-being and heart health. Compensation provided.

Do you have advanced melanoma that has progressed on treatment? Do you have a tumor longer than 1cm in length? If so, you might be able to take part in a study that compares a study treatment (Vusolimogene Oderparepvec and Nivolumab) with your physician's choice of standard of care treatment. Compensation provided.

Have you been diagnosed with hormone receptor (HR+) and human epidermal growth factor receptor 2 (HER2)-negative recurrent or metastatic breast cancer? If so, you may be eligible for a clinical trial investigating the combination of endocrine therapy with alisertib.

Have you been diagnosed with cancer. If so, you may be able to take part in a research study looking to improve cancer care for patients whose treatment outcomes have led to challenges in their quality of life.

Do you have moderate Parkinson's disease with motor symptoms? Are you over 45 years old? You may be able to participate in a research study to find out if a new treatment involving surgery can help with your symptoms. Compensation provided.

Does hypertonic saline improve mucus clearance in bronchiectasis? The purpose of this research study is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lungs in people with bronchiectasis. We will compare mucociliary clearance (MCC: a measurement of the rate at which a person's lungs can clear inhaled particles) at baseline, after a single dose of HS, and after two weeks of treatment with HS twice a day. We will also assess response to HS with other outcomes (spirometry, multiple breath washout [MBW], changes in sputum [coughed up mucus or phlegm], and survey responses). Compensation provided. No blood draws required.

Are you a patient with advanced basal-like pancreatic adenocarcinoma? If so this could the a Trial for you to as this is a Phase I/II trial is to evaluate the safety, efficacy and tolerability of low-dose EGFR inhibitors in combination with bi-weekly gemcitabine/nab-paclitaxel (GnP) in subjects with basal tumors