The purpose of this research study is to assess the patient-level, healthcare provider/system-level, and community-level barriers to resolving abnormal mammograms and initiation of treatment of breast cancer in the 3 geographic regions of North Carolina: the greater Charlotte area, the Northwest, and the Northeast. These areas include the following counties: Anson, Cabarrus, Cleveland, Gaston, Lincoln, Mecklenburg, Stanly, Union, Edgecombe, Halifax, Nash, Northampton, Wilson , Ashe, Alleghany, Surry, Stokes, Watauga, Wilkes, Yadkin, Forsyth, Avery, Caldwell, Alexander, Iredell, Davie, Davidson, Burke, Catawba, and Rowan. These barriers can include obtainment of biopsies and other diagnostic procedures for resolving abnormal mammograms abnormalities or breast symptoms, access to care providers after breast cancer diagnosis, and initiation of appropriate surgical, chemotherapy, and radiation treatments after diagnosis.

The purpose of this study is to find out if and how family members may impact weight loss in men enrolled in a weight loss intervention. This information will be used to improve family based weight loss programs.

You are being asked to take part in this study because you previously agreed to receive a U.S. Food and Drug Administration (FDA) approved drug, idecabtagene vicleucel (ide-cel), for the treatment of your disease as part of routine care and not a clinical research study. You had the blood collection (leukapheresis) (pronounced loo-ka-fer-ee-sis) procedure, your T cells (a subset of your white blood cells that are part of your immune system and attack things like infections and cancer cells) were collected and genetically modified in a laboratory in order to manufacture the ide-cel T cells for your disease treatment. The ide-cel T cells that were produced do not meet all of the prespecified release criteria to be used as a routine prescription drug as required by the governing health authority (such as the FDA) where you are being treated. For example, the modified T cells may have a lower cell

This study aims to understand how rural women experience the expansion of oil palm crops, particularly in the Colombian Llanos region. The research will delve into the work women performed in the plantations and on their own farms. The study also wants to address how women interact with their environment (their practices, what they know about nature, how they use nature) and if that has changed because of the expansion of oil palm. Finally, the research will also explore how the government is helping those women and their families to achieve their dreams. This research is important because there is very little information about rural women living in this region in Colombia. My research will contribute to know more about their stories and highlight their important contribution to the country.

This phase 3 trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated low-grade glioma (LGG) that does not have a genetic abnormality called BRAFV600E mutation and is not associated with systemic neurofibromatosis type 1. Selumetinib works by blocking some of the enzymes needed for cell growth and may kill tumor cells. Carboplatin and vincristine are chemotherapy drugs that work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. The overall goal of this study is to see if selumetinib works just as well as the standard treatment of CV for patients with LGG. Another goal of this study is to compare the effects of selumetinib versus CV in subjects with LGG to find out which is better. Additionally, this trial will

The purpose of this study is to lay the groundwork for a pragmatic trial and real-world implementation of Mouth Care Without a Battle (MCWB) for assisted living (AL) residents with dementia and their caregivers. The aims are to refine MCWB for AL, and examine research efficacy (working with a research dental hygienist) and real-world efficacy (working with community public health dental hygienists) to train personal care aides in 48 AL communities across North Carolina to provide mouth care.

To compare treatments of bone cysts between typical treatment and that with Vitoss morsels

Describe maternal and neonatal outcomes among a cohort of pregnant and postpartum women with OUD who experienced incarceration during pregnancy

The purpose of this research study is to understand how the monitoring of Patient-Reported Outcomes (PROs) could help improve surgical care for patients undergoing chest surgeries. PROs are symptoms directly reported by patients through the completion of a survey.

Collect a bank of respiratory samples from pediatric patients with airway infection, particularly viral infection. Analysis of these samples should help us develop new treatments for airway infection in children.