This study is trying to learn more about a medication called sparsentan, and how it can help the kidneys filter protein and slow the decline of kidney function. The amount of protein found in the urine (called proteinuria) is seen as a marker of kidney function. Lowering proteinuria levels is associated with better kidney health outcomes.
We still have a lot to learn about why people develop glomerular disease and what the best medicines are to treat these diseases. Diabetes is a common, chronic illness and many people with glomerular disease also have diabetes. Currently, there is no information telling us the best ways to treat patients with both diabetes and glomerular disease, or how to counsel them about prognosis and risks for complications. This substudy of the Cure Glomerulopathy Network brings together information and laboratory specimens from patients with diabetes and glomerular disease to speed up and improve health research for their care.
The purpose of this research project is to learn about whether a personalized eating plan designed specifically for teens with type 1 diabetes will help them better manage their blood sugar. This plan will be individualized to teens' unique preferences and daily routines. A dietician will provide ongoing support to the teen and family throughout the project
The CureGN Network acts as a "library" of data for investigators across the world to use to help us ask the following questions: 1) What is the disease?; 2) Why did it happen to me?; 3) Can it be passed down to my family members?; 4) What treatments work the best with the least side effects?
This is a three-year research study for people with primary membranous nephropathy (primary MN). The study will test if combining belimumab and rituximab is effective in treating Primary MN.
To evaluate the safety and efficacy of a device removing lipids from the blood using an apheresis device in treating primary FSGS
If you have been treated with ANCA vasculitis and you are now in remission, you may be able to participate in a study to test if a specific blood test can help your doctor decide if you need maintenance therapy.
The purpose of this study is to learn more about three kidney diseases called nephrotic syndrome: Focal Segmental Glomerulosclerosis (FSGS), Minimal Change Disease (MCD), and Membranous Nephropathy (MN). By collecting health information and laboratory samples from individuals who have these diseases and by making this information available to researchers, we hope to gain new knowledge about these diseases and to find better treatments for them.
We are looking for patients with kidney disease and healthy controls (no kidney disease) to provide blood samples, fill out surveys, and provide health related information to help investigators learn more about how to better diagnose and treat kidney disease. The information you provide will go into a "library" of data for doctors and researchers across the world to use for research projects. If you are a kidney patient, we are able to use your information to find out if you are eligible for treatment studies/other studies in the future.
The purpose of this research study is to monitor how well patients with fatty liver disease can follow clinician-recommended diet and exercise before their liver surgery. Our goal is to understand patient adherence to weight-related goals, weight loss, physical activity, and improved liver health. You are being asked to be in the study because you are a patient with fatty liver disease planning to have liver surgery.