The purpose of this study is to understand if a new oral medication (pill) can be used to treat depression in people who have not felt relief from other anti-depression medications.

We want to improve emergency stroke care across the state of North Carolina. We are doing this by gathering information from individuals like you about emergency stroke services. Your perspective as a stroke patient or caregiver to a stroke patient in North Carolina will help us identify challenges in stroke care and develop effective solutions for those challenges.

Do you want to share your journey of overcoming addiction and nurturing a positive environment for your child? We are listening. If you or your partner are a parent in recovery with a child aged 6-12, you may be able to participate in a study that helps families facing similar challenges. Compensation and childcare will be provided.

Are you living with HIV? Do seek your care at the UNC Infectious Diseases Clinic? If so, you are eligible to participate in Database study! Participating is at no expense to you, and there are no study visits. You would be contributing to increasing knowledge about HIV and furthering the HIV research field.

In this study, I want to learn more about the firsthand experiences of people living with OCD. This includes their thoughts, rituals, and beliefs. It also includes their self-perception, as well as their recovery journeys. These personal stories will help me learn more about how people with OCD express their fears, anxieties, and values.

This study is for patients diagnosed with breast cancer that has spread to other parts of the body, which is called Metastatic Breast Cancer. This study will look at information from your tumor that may help choose treatments. Researchers will use this information to find out how different patients may respond to different treatments, leading to better treatments for future patients. You may not benefit personally, but your doctor may be given information which may help guide your treatments.

Are you 18 or older? Have you recently received a diagnosis of acute myeloid leukemia (AML) with certain gene changes? If you answered yes to both, you may be able to participate in an AML treatment study. We want to understand the effectiveness of the combination of a new anti-cancer drug called SNDX-5613 and the standard chemotherapy treatment.

The purpose of this research is to examine how listeners access and learn speech when listening in clear or challenging conditions. We are currently recruiting adults with normal hearing. Research participants may be asked to complete listening tasks, complete questionnaires, and complete sleep tracking measures. The research study is expected to take 7 days of participation and will be completed with 2 in-person sessions. The goal of this research is to contribute to a better understanding of how listeners learn new speech signals, and in so doing, point to rehabilitation considerations for listeners with hearing loss.

Are you a young adult ages 18-24 who identifies as LGBTQ+, speaks English, and lives in North Carolina? You may be eligible for a 1-time interview to help us understand diverse voices and perspectives on experiences of sexual identity management and well-being among LGBTQ+ young adults. Participants who complete the interview will receive a $40 virtual gift card.

In this study, we are looking at patterns in certain blood proteins. We want to understand how a protein supplement called β-hydroxy-methyl-butyrate (HMB) works in older adults who feel tired or have less muscle strength.