We're testing a new treatment called AVZO-103, alone and with another drug, to find the safest and most effective dose. We want to see if this combination can help treat advanced solid tumors. We're also studying how your body processes and reacts to AVZO-103 to learn who might benefit most from it.
We're exploring how adults with autism in North Carolina view themselves and each other. We want to learn if there's a sense of community among them and how their thoughts have evolved.
Have you had trouble getting your child's asthma medication filled at the pharmacy? Have you been inconvenienced because of problems with the prescription, lack of insurance coverage for the drug, or need for a prior authorization? We want to hear from you about the problems you've faced and how we can make getting your child's asthma medication easier and more convenient. We are conducting a research study of caregivers that involves one virtual discussion session with a researcher and other caregivers of children with asthma. You will be compensated for your time.
Do you have Stage III or IV Squamous Cell Skin Cancer that is considered high risk? If so,you may be able to take part in a research study evaluating combination therapies versus the standard approach for your type of cancer.
Are you between the ages of 18 and 35 or 65 and 85? Are you interested in contributing to research that wants to understand how human memory works? If so, you may be able to take part in a study on how younger and older adults learn and remember words. You can help us learn more about how memory works in adults! Compensation provided.
Do you feel like your mood is affected by your menstrual cycle? Do you feel like your social media use changes depending on your mood? If you experience a regular menstrual cycle, you may be eligible to participate in a research study to better understand the factors that influence mood and social media use across the menstrual cycle. Compensation provided.
Have you been told you have cervical cancer and are getting ready for radiation therapy? You might be able to join a study that tests a special gel called Barrigel during your treatment. This gel could protect your healthy organs from the effects of radiation, making your treatment safer and possibly with fewer side effects. If you join, a doctor will use Barrigel to create space between your cervix and rectum during your cancer treatment. This has been used with prostate cancer patients to keep healthy tissues safe from radiation. Our study wants to see if it works well for people with cervical cancer too.
MOON101 is being developed to treat patients who suffer from peanut allergy and to improve the overall safety and efficacy compared to other available treatment routes. Potential advantages of MOON101 include an anticipated lower applied dose of peanut allergen compared to other products. The MOON101 system delivers peanut allergen via a microneedle (MN) stamp. Microneedle technology is similar to a skin prick test (SPT), which is very well tolerated. The consistent dose delivery should enhance efficacy of the stamp and reduce variability in response. Improvement in safety coupled with improved efficacy is the goal of this product.
You are being asked to take part in this study because you have triple negative (TN) breast cancer that has spread to your lymph nodes. You are also planning to get chemo-immunotherapy treatment before surgery. Radiation therapy (RT) has been shown to improve the body's immune response against tumors when it is given with a drug called pembrolizumab. The purpose of this study is to find the best and safest dose of radiation (low or high) when given with pembrolizumab. Radiation is measured in Gy (pronounced "gray"). You will be randomly assigned (like flipping a coin) to receive either a low dose RT boost (9 Gy) or a high dose RT boost (24 Gy). The RT will be given with one dose of pembrolizumab. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.
Do you identify as queer? Are you currently family planning? You may be eligible for our study. We are interested in understanding how stress and social support during family planning are related to health outcomes in queer parents and their infants. Study participation will includes interviews, survey completion, and fecal and skin microbiome collection. Compensation provided.