You are being asked to take part in this study because you have triple negative (TN) breast cancer that has spread to your lymph nodes. You are also planning to get chemo-immunotherapy treatment before surgery. Radiation therapy (RT) has been shown to improve the body's immune response against tumors when it is given with a drug called pembrolizumab. The purpose of this study is to find the best and safest dose of radiation (low or high) when given with pembrolizumab. Radiation is measured in Gy (pronounced "gray"). You will be randomly assigned (like flipping a coin) to receive either a low dose RT boost (9 Gy) or a high dose RT boost (24 Gy). The RT will be given with one dose of pembrolizumab. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.

We are testing the usability of a health information website that shares easy-to-understand information about prostate cancer. The website is called iPICS. We want to see if the website is helpful for people living in rural areas, especially older adults. By working with public libraries, we hope to learn how to make the website better and easier to use. Our goal is to help people find trustworthy health information so they can make good decisions about their health.

If you have Autosomal Dominant Polycystic Kidney Disease (ADPKD), you can help us find out how a new investigational drug works for people like you. Joining this study might not help you directly, but it could help others in the future.

Are you a patient with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL)? If so this could be the study for you. The purpose of this study is to investigate if the sonrotoclax in combination with obinutuzumab or rituximab works better and is safe in participants with

This study is researching the effect of 20 mg Vonoprazan compared to placebo on the treatment of EoE. For those diagnosed with EoE and are interested in a pill treatment study.

We're doing this study to explore how a device called TheraBionic affects people with liver cancer and their condition. This device uses special frequencies to target cancer cells and is being tested for treating advanced liver cancer.

I will be interviewing folks who attend free live music events to understand how they view themselves in the community and how they experience religiosity in secular society.

The purpose of this study is to assess the usefulness of an app designed to reduce alcohol use and related harms among young adults.

Do you work in a white-collar occupation? Are you interested in how your occupation affects your fatigue? If so, you may be eligible to participate in a research study that explores how one's occupation affects their ability to perform a physical task under stress. Participants will receive a body composition scan.

This study will use prenatal and postpartum interviews to understand people's birth expectations and desires before they give birth and how their experience matches up to their actual experience. I am interested in how expectations influence how people navigate their prenatal care and how this influences the birth experience. This study will take place in the Appalachian region. Participants will also have the option to provide a hair sample and a urine sample from their infant at 3 months if they wish to look at how these experiences affect stress hormones.