The standard treatment for newly-diagnosed multiple myeloma (NDMM) is autologous stem cell transplantation (ASCT). For this procedure, a patient's own healthy, blood-forming cells are collected. The patient then receives high-dose chemotherapy or radiation to kill the cancer cells. Then their healthy cells are returned to their body to recover. While ASCT is effective for many patients, it has significant side effects and may not be the best option for every patient with NDMM. In this research study, participants will receive one of two (2) study treatments: a new regimen of elranatamab plus daratumumab or a conventional regimen of ASCT plus lenalidomide and daratumumab. The delayed use of ASCT, as explored in this research study, is experimental and not standard-of-care.
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We are doing this study to find out which type of shoulder surgery and rehab plan works best for certain kind of shoulder problem called anterior shoulder instability with mild bone loss. We want to see which surgery helps the shoulder heal strongest and gets people back to work or sports safely. We'll also look at what factors might raise the risk of problems after surgery, so doctors can better guide future patients.
Are you having foot fusion surgery? Join our study to help us learn how people heal and move after this kind of surgery. Your experience could help improve care for others with foot arthritis.
Do you have a shoulder or arm injury diagnosed with an MRI? Or are you healthy and active? Join our study to help us learn how well ultrasound works compared to MRI for finding muscle and tendon problems. Your help can improve sports injury care in the future.
Are you having rotator cuff surgery? You might be able to join a research study. This study is looking at BioEnthesis, a new surgical tool that might help your shoulder heal better. Joining this study could help improve care for other patients in the future.
Had shoulder replacement surgery? Help us learn how long implants last and how well they work over time. We're tracking patients with shoulder replacements to better understand results years after surgery. Your experience can improve care for future patients.
This study explores how parenting behaviors and early-life stress may shape a child's brain and behavior. We are inviting parents of children aged 0-5 to share information through a short survey. Some families may be invited to try out a new early learning toolkit designed to support their child's development.
We are conducting a study to see how money concerns can affect people with advanced cancer. The goal of this study is to see if monthly check-ins about money problems help ease financial worries for adults with advanced cancer who are getting treatment. If you or someone you know is dealing with money stress while having cancer, we'd like to hear from you. Your participation can help improve care for future patients.
The purpose of this study is an initial pilot study to develop the safety, feasibility, and tolerability of a new type of individualized transcranial alternating current stimulation (tACS) to treat antenatal depression, which delivers personalized stimulation waveforms based individual participant EEG activity. In the first Phase of this study, we are investigating this intervention in healthy control participants.