Leveraging our decades of experience studying the acute and chronic effects of traumatic brain injury (TBI) and concussion, our investigative team propose an innovative, translational approach that bridges both preclinical and clinical studies. We propose testing multiple potential preventative and therapeutic strategies in the preclinical setting, while simultaneously conducting a prospective, longitudinal study of neurologic health outcomes associated with concussion and sub-concussive exposure in former NFL players. Our prior studies of former NFL players over the past 15 years provide us with a unique opportunity to conduct a truly prospective, longitudinal study of long-term neurologic health outcomes and determine any possible association with concussion and repetitive sub-concussive exposure. In parallel, we have developed animal models of repeated concussions (repetitive mild TBI [rmTBI]) and chronic traumatic encephalopathy (CTE). We have studied the effects of readily translatable preventative and therapeutic strategies, including the N-methyl-D-aspartate (NMDA) receptor antagonist memantine, low dose carbon monoxide

In this study, we want to learn more about the experiences and activities of high school-aged youth after a neurological event. This study will also help us to understand the perspectives of youth and a parent/caregiver through photos and stories.

The purpose of this screening study is to collect samples to learn more about your cancer using two investigational diagnostic tests. We will use the results to find out if you meet the eligibility criteria and could enroll in a separate TScan treatment research study.

We want to learn more about how executive functioning differs between children with ADHD, ASD, or neither. We have finished recruiting for our ADHD and typically developing groups but are still recruiting autistic children to be a part of our study. Children will complete an iPad-based measure of executive functioning and complete various tasks while their brain activity is being monitored using EEG. We will also complete a short eye-tracking task. Parents will fill out different forms to get an understanding of each child's developmental history and current behaviors.

Have you been diagnosed with Low Risk Breast Cancer? Have you already been treated with surgery? If so, you may be able to take part in a research study looking at the effect of regional nodal radiotherapy.

The purpose of this study is to learn more about factors that contribute to exercise-induced fatigue in women.

Learn more about the learning experiences of undergraduate students when they take Asian Studies courses in order to improve the engagement of students in the future.

If you or your child had or currently have abnormal cell growth or a related condition, including brain and nervous system tumors, you may be able to take part in a research study. This is a study for patients who are receiving treatment at UNC hospitals. In this study, we will collect samples to better understand the causes of your disease.

Nowadays, AI systems have been applied widely in a variety of predictive tasks, from objective detection to text classification. These AI systems have greatly advanced automated decision-making. However, sometimes humans and AI systems think in very different ways, which means humans and AI systems might use different evidence to make predictions. In this study, we are using sentiment analysis of Amazon product reviews as a case study. Humans will judge sentiments of different words with different AI explanations. Human and AI judgments will be compared to find to which extend human and AI knowledge align.

This is a research study to learn about how mothers in recovery from addiction define, recognize, and foster emotions that connect their children to others such as gratitude, generosity, and love. People enrolled in the study will meet with a study team member in groups of 3-5 to complete an online survey and focus group interview asking for your opinions about these issues. The group meeting will take place at or near a treatment or recovery center and take about 90-minutes. Meetings can be in-person or virtual.