The purpose of this research is to compare any good and bad effects of using radium-223 along with docetaxel chemotherapy treatment versus using docetaxel alone. The addition of radium223 to docetaxel could be a better cancer treatment than just docetaxel alone, but it could also cause additional side effects. This study will allow the researchers to know whether this different approach is better, the same, or worse than the usual approach.

Have you been diagnosed with uterine cancer called endometrial serous carcinoma or carcinosarcoma? If so, you may be able to take part in a research study to test if adding a drug or drugs that target HER2 proteins in addition to the usual combination of chemotherapy drugs could prevent your cancer from returning or shrink your cancer.

We're all different. But when we visit the doctor, our treatments are often the same. We think one day health care should be tailored for you. This is called precision medicine. And research can help us get there. Taking part in the All of Us Research Program involves sharing information about your health, habits, and what it's like where you live. If you are 18 or older and live in the United States, you may be able to take part!

Are you receiving initial treatment for non-small cell lung cancer or invasive squamous cell carcinoma of the head and neck and want to participate in research that aims to improve treatment and care of future patients with the same diagnosis? If so, you may be able to participate in a study for an investigational blood test to predict whether your cancer will come back.

Do you have known or suspected lung and/or head and neck cancer? Are you scheduled for a tumor biopsy? If so, you may be able to participate in a research registry aimed at learning more about lung and head/neck cancer.

In this study, we want to learn more about the safety and effectiveness of using a personalized vaccine with a drug called pembrolizumab for the treatment of non‐small cell lung cancer (NSCLC) and squamous cell cancer of the head and neck (SCCHN).

We are doing a study to help us adapt a physical activity program for adults with intellectual disabilities. We are looking for adults with intellectual disabilities, parents/caregivers, support staff, and exercise professionals to complete a survey and take part in interviews or focus groups to provide feedback on a physical activity program. The program includes weekly group fitness meetings, one-to-one coaching meetings, and an app to support setting, monitoring, and achieving exercise goals.

Have you been diagnosed with small cell lung cancer? Is your current treatment no longer working in controlling your cancer? If so, you may be able to take part in a research study looking at giving trilaciclib to help minimize the side effects of lurbinectedin.

This is a Phase III study to help us improve outcomes of patients with ER+/HER2- early breast cancer with intermediate or high risk for disease recurrence. This study is for patients who have completed definitive locoregional therapy and standard adjuvant endocrine therapy for at least 2 years and up to 5 years without disease recurrence. In this study, we want to learn if a new oral "SERD" therapy called Camizestrant is helpful in reducing chance of recurrence. Talk to your Medical Oncologist for more information about this trial.

People with Parkinson disease often develop difficulty walking. Metronomes are thought to help improve walking. We believe that setting metronomes slower while walking on a treadmill and faster when walking over the ground may target certain portions of gait. Our goal is to create beneficial changes in the way that people walk that persist and can be seen in the long-term.