The purpose of this study is to learn more about three kidney diseases called nephrotic syndrome: Focal Segmental Glomerulosclerosis (FSGS), Minimal Change Disease (MCD), and Membranous Nephropathy (MN). By collecting health information and laboratory samples from individuals who have these diseases and by making this information available to researchers, we hope to gain new knowledge about these diseases and to find better treatments for them.
We are looking for patients with kidney disease and healthy controls (no kidney disease) to provide blood samples, fill out surveys, and provide health related information to help investigators learn more about how to better diagnose and treat kidney disease. The information you provide will go into a "library" of data for doctors and researchers across the world to use for research projects. If you are a kidney patient, we are able to use your information to find out if you are eligible for treatment studies/other studies in the future.
Researchers are looking for current and former smokers with or without COPD to enroll in a registry to be contacted for future studies.
Do you have probable Dementia with Lewy Bodies (DLB), Mild Cognitive Impairment with "high likelihood" DLB, or Parkinson's Disease Dementia (PDD)? You may be able to participate in an observational study to track your disease progression and promote future research.
The purpose of this study is to establish a safe dose of study cells (ALTCAR.CD30) to give after chemotherapy and estimate progression free survival in pediatric patients with CD30+ refractory/relapsed Hodgkin lymphoma (HL) and non-Hodgkin lymphoma.
Do you have bladder, kidney, prostate, or another genitourinary cancer diagnosis? If so, you may be able to take part in a research study collecting specimens (e.g., blood, urine, saliva, tissue) during your already scheduled appointments. Collecting these specimens may help researchers develop new ways to detect cancer earlier or to more effectively treat cancer.
Functional Electrical Stimulation (FES) is a commonly prescribed technology for restoration of limb function and muscular rehabilitation. FES works by artificially stimulating muscle fibers to generate a contraction. However, one of the main issues with the use of FES is the rapid onset of muscle fatigue, which makes it difficult to perform long-term periodic motions such as walking. Recent research has shown methods successful at mitigating the impact of muscle fatigue using multiple electrodes. Instead of using the traditional approach of two FES pads targeting a specific muscle group, this study will use multiple electrodes and cycles the order in which the electrodes are stimulating thus targeting specific muscles within the muscle group and reducing the muscle fatigue. However, how to optimize the current through multiple electrodes is not known yet. This study will help determine the optimization of multiple electrodes for reducing fatigue.
The research team from the Carolina Global Breastfeeding Institute is conducting a study on the implementation of IYCF-E in Western North Carolina (WNC) after Hurricane Helene. This research aims to share lessons learned and improve the quality of future relief efforts through: 1) sharing lived experiences; 2) assessing effectiveness of training; and 3) informing the state- and national-level policy recommendations for incorporating Infant and Young Child Feeding in Emergencies (IYCF-E) evidence-based practices.
To compare the prevalence, severity, and timing of chronic health conditions (CHC) in a cohort of patients with DS-AL (Down Syndrome Acute Leukemia) with age-comparable DS individuals that have no cancer history. Our secondary objectives will compare NP (Neuro-Psychological) and health-related quality of life outcomes in survivors of DS-AL compared with age-comparable DS individuals with no cancer history, and will identify risk determinants of CHC and NP late effects among survivors of DS-AL.
This implementation science study will use mixed methods and an interrupted time series design to evaluate an implementation strategy intended to expand the reach and effectiveness of COVID-19 testing and vaccination services in underserved populations in the Piedmont region of NC. The primary service outcomes (i.e., reach and effectiveness) will be evaluated using review of existing routinely collected data. The primary implementation outcomes will be assessed through mixed methods research with patients who received, and providers who delivered, COVID-19 testing or prevention services, such as vaccination, at a Consortium-supported site such as a Federally Qualified Health Center administered by Piedmont Health. A standardized script will be used to inform potential participants about the study, their research options, and to screen to see if they are preliminarily eligible to take part in the study.