Systematic reviews (SRs) of healthcare interventions should identify patient safety concerns; however, many SRs are designed to assess benefits, and preliminary evidence suggests that conclusions about harms in SRs might not be trustworthy. Using >19,000 SRs of drugs for which we have full texts (including >4,000 overlapping reviews), and using innovative methods for analysis (e.g., natural language processing), we will examine whether information about safety in SRs is consistent, whether SRs address safety concerns identified using real-world evidence, and whether SRs are consistent with safety information on drug labels. Based on best evidence, including findings from this study, we will develop contemporary guidance for synthesizing and reporting safety information in SRs.
This study is meant to test how effective the Laguna system is at treating pulmonary embolism.
Analyze how usage of a visualization tool that provides data quality analysis can affect a data scientist's workflow during data preprocessing
The purpose of this study is to learn about how hospital-based doulas impact the birthing experience.
Some people living with HIV can have chronic lung and breathing issues. We want to learn if the immune system of the nose may lead to these problems. We will collect a sample from the nose using a small strip of paper put in the nose for two minutes. This sample will be tested for inflammation and bacteria. We will do this test in 150 people with HIV and 100 without HIV. We will ask 100 people to come back in 6 months to do the sample again.
The purpose of this study is to understand the planning and implementation process of the Summer EBT program in Rhode Island and North Carolina.
This study aims to evaluating the usage and impact of the novel UNC Faculty-developed teaching tool, Immunology Mapping
This project is studying the effect of pediatric care coordination on the behavioral health of children and parents.
The objective of this study is to understand dental student perceptions of providing dental treatment to marginalized groups as well as willingness to accept Medicaid to improve health equity.
To evaluate whether different biomarkers can stratify patients with newly diagnosed GBM that have progressive enhancement within 12 weeks post-XRT into risk groups based on overall survival.