TCN PATHS is a Justice Community Opioid Innovations Network (JCOIN) study in collaboration with UNC-CH, Yale, The University of Puerto Rico, The Hennepin Research Institute, University of Rochester, University of Connecticut, Albert Einstein College of Medicine, and the University of Miami, aims to improve health outcomes for justice involved persons with Opioid Use Disorder (OUD). Opioid overdose is the leading cause of death, and a common cause of morbidity, after release from jail. Recently, because medications for OUD effectively reduced relapse, recidivism and overdose, several jails have started to treat OUD with medications. However, OUD treatment discontinuation upon release is a persistent problem. The long-term goal of the study is to reduce morbidity and mortality from OUD among justice-involved individuals. The overall objective is to assess whether the Transitions Clinic Network (TCN), which provides enhanced primary care for people released from incarceration in 30 community health centers in the United States,

This research uses the Attitudes Related to Trauma-Informed Care (ARTIC) Scale to gauge the readiness of school mental health practitioners (i.e., school psychologists, social workers, and counselors) to shift toward trauma-sensitive systems. Despite the reliance on school mental health practitioners in this movement, little research exists on their preparedness for and training in trauma-informed approaches. In hope of better situating schools to act as buffers against the adverse effects of childhood trauma, this research seeks to inform graduate and professional-level training on disciplinary practice, causes of student behavior, and the protective nature of secure adult relationships.

The purpose of this research study is to evaluate the effects of Sickle Cell Disease on the state of coagulation and effects on generation of certain coagulation proteins. People with sickle cell disease tend to have a higher rate of thrombosis which is not fully understood. Through this study, we hope to gain a better understanding of the effects of sickle cell disease on turning on coagulation that ultimately leads to a thrombotic event.

The purpose of this study is to collect information through online surveys and interviews with college students and faculty/staff to help inform the development of a nutrition and culinary education curriculum for college students.

While the identification of autism in females has steadily increased, there remains a critical gap in our understanding of female specific issues for autistic females , such as menstruation, pregnancy, motherhood, and menopause. Menopause marks a key reproductive transition period for females. The purpose of this study is to characterize mental health challenges and experiences during the menopause via a three-pronged, mixed methods study, employing a large scale online survey followed by in-depth interviews and daily diaries across a complete menstrual cycle.

This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed). Down syndrome patients with relapsed B-ALL are included in this study. Blinatumomab is an antibody, which is a protein that identifies and targets specific molecules in the body. Blinatumomab searches for and attaches itself to the cancer cell. Once attached, an immune response occurs which may kill the cancer cell. Nivolumab is a medicine that may boost a patient's immune system. Giving nivolumab in combination with blinatumomab may cause the cancer to stop growing for a period of time, and for some patients, it may lessen the symptoms, such as pain, that are caused by the cancer.

We propose to develop and test health messages about e-cigarettes and study their impact. Findings will inform e-cigarette warning policies and communication campaigns.

Gather detailed information on the health and treatment of patients with severe asthma worldwide, track how well patients are responding to treatment, and undertake medical research using data from the registry to improve asthma treatment and care.

To evaluate the impact on learning patient-centered care in the context of trauma assessments using a virtual reality educational compared to a traditional powerpoint tool.

The purpose of this study is to learn more about the lining of the uterus, called the endometrium, by taking samples of endometrial tissue. Samples are taken by a common procedure called an endometrial biopsy. We will look at markers of inflammation and altered energy metabolism in people with and without endometriosis in order to better understand the disease and identify new and better ways to treat endometriosis.