Have you diagnosed with lymph node positive early breast cancer, have received surgery, and have not received any systemic or radiation treatment prior to surgery? If so, you may be able to take part in this clinical trial which seeks to improve the treatment of early-stage breast cancer by examining ctDNA, a biomarker found in the blood that may indicate the presence of disease. This study aims to determine if ctDNA can help doctors personalize therapies leading to more effective treatment plans.

Do you or your child have alopecia areata? Would you be interested in hearing more about a clinical study on alopecia areata? If so, you may be able to participate in a research study to find out how effective and safe the study medication ritlecitinib is in patients with alopecia areata.

Preventing walking disability in our rapidly aging population is an enormous public health challenge. Fundamental to their loss of functional mobility is that the muscles needed to power walking experience decline in function with age. Wearable assistive devices can be designed to augment the function of these muscles and may make walking easier. If you are a healthy older adult, you may be able to participate in a training intervention to determine the feasibility of a passive wearable ankle device that strengthens walking dynamics and decreases fall risk.

Most patients with generalized Myasthenia Gravis need treatments that carry substantial risk of side effects and toxicity, Descartes-08 is a cell therapy is a RNA based CAR-T that causes direct killing of target cells without serious generalized toxicities.

Do you have chronic limb-threatening ischemia? This might cause you pain, slow-healing wounds, or make it hard to decide about surgeries and treatments for your leg or foot. We want to hear from you. What has getting the care you need been like? Have you ever felt unsure about your treatment options or needed more support? Sharing your story can help us make care better for others with the same condition. It might help doctors to explain things more clearly, find better ways to manage pain, or support people who worry about their independence. We will talk with you two times-now and again in six months-to hear about your experiences. Your story can help make care easier and better for people in the future.

Have you had a stillborn baby or delivered a baby before 35 weeks? You might be able to join the ADEPT study. These situations can make your current pregnancy higher risk. Doctors often suggest taking aspirin to help. This study wants to find out if taking a higher dose of aspirin works better to lower the risk of having another preterm delivery or stillborn baby.

Have you been diagnosed with Metastatic Colorectal Cancer? If so, you might be able to take part in a study to see if an investigational product is safe and effective for treating metastatic colorectal cancer.

We want to hear from you! If you are a college student, please take our quick survey. It will take about 15 minutes. We want to know how you feel about being part of our campus. Your answers are private. You can also enter to win a $20 Amazon gift card. We have 50 gift cards to give away! You don't have to do the survey to enter the raffle.

Is your toddler not talking? Do they show signs of possible autism? Does your family qualify for public assistance (WIC, Medicaid, etc.)? If so, you may be able to participate in a study about how your child develops communication skills. We will do in-home assessments of your child's communication at 3 timepoints over a year and give you reports of your child's development and autism traits that can be used to access services. Compensation is provided.

Feel anxious when your body goes into "fight or flight?" You may be eligible to participate in a research study to learn how difficult emotions, such as anxiety and fear, relate to feelings in the body. Compensation provided.