Do you have AML, ALL, or MDS, and are preparing for a stem cell transplant from an unrelated donor? If so, you might be able to take part in a study to will see if a reduced dose of a drug called cyclophosphamide will still reduce your chances of developing Graft versus Host disease, but also lower your chances of side effects from the drug.

The study treatment, finerenone, is being developed to help people who have long lasting kidney disease, also known as chronic kidney disease (CKD). It works by blocking a certain hormone called aldosterone that causes injury and inflammation in the heart and kidney which is known to play a role in CKD. In this study, the researchers want to learn if finerenone works the same way in kidney transplant recipients. Some subjects will receive the study drug and some will receive a placebo.

Do you have pancreatic ductal adenocarcinoma that has come back after receiving standard therapy? If so, you may be able to participate in this gene therapy research study to learn more about using you own modified immune cells as possible treatment.

Have you been diagnosed with a B cell disease that has returned after your previous treatment or is not responding to your current treatment? If so, you might be able to take part in a study to see if a new treatment is safe and can help treat people with B-cell diseases.

Have you been diagnosed with multiple myeloma? Have you been prescribed daratumumab for the first time? You may be able to take part in a research study to help us learn more about severe and fatal infusion-related reactions in patients with multiple myeloma.

Have you ever wondered what environmental toxins you are exposed to on a daily basis, and how it might affect your health? The STRIVE study is looking for volunteers who would like to provide blood, urine, and/or saliva, as well as home samples such as soil, dust, and/or water. In this study, we want to learn more about the environmental factors that contribute to advanced liver disease and liver cancer. We are looking for healthy volunteers and people with liver cirrhosis who live in either North Carolina or Georgia to take part.

Do you have Non-Small Cell Lung Cancer? Have you previously been treated with Osimertinib? If so, you may be eligible for a trial comparing osimertinib in combination with other medications to treat your lung cancer. Please reach out if you're interested!

Have you been diagnosed with early stage triple negative breast cancer? We are asking you to take part in this research study because you have been diagnosed with triple-negative breast cancer (TNBC) and have recently completed preoperative chemotherapy in combination with pembrolizumab, followed by breast surgery. The chemotherapy plus pembrolizumab produced a pathologic complete response (pCR), meaning that no remaining cancer was found during your breast surgery.

Do you have a child between 12-14 years of age who is healthy but has some symptoms of anxiety or unexplained nervousness? You may be able to take part in a study with your child to better understand how anxiety develops across adolescence in brain and stress responses. Compensation provided.

Learn if voice recognition technology can help in the early detection of memory problems We are inviting you to participate in a research study, Exploiting Voice Assistant Systems for Early Detection of Cognitive Decline, by completion of a virtual interaction involving a memory test, questionnaires, and interaction with Chat GPT and an Amazon Alexa. Our study team is seeking volunteers: • Aged 65 and older • Are healthy or have mild cognitive impairment • Have access to Wi-Fi and a quiet environment • Have the internet browser Google Chrome or are willing to install it on their personal computer This study involves: • 1 Zoom session • Completion of memory tests and questionnaires • Interaction with Amazon Alexa • Interaction with Chat GPT • Virtual visit will be audio and videotaped After the session, you will be compensated $20 for your participation.