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UNC-Chapel Hill Division of Endocrinology and Metabolism

21 studies match your search
Not currently enrolling

Diabetes study for patients with diabetes and renal impairment who are currently using basal insulin with or without Metformin or SGLT2 inhibitors

This study aims to investigate the effectiveness and safety of retatrutide, a new diabetes medication) at doses of 4 mg, 9 mg, or 12 mg that will be taken as a weekly injection for about 1 year, compared to a placebo. A participant's change in HbA1c level will be primary outcome of interest. We are seeking participants with type 2 diabetes that has affected kidney function and are currently taking long-acting insulin with metformin and/or a SGLT2 inhibitor.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
Open

Type One Diabetes and Hypoglycemia Study

Do you have type one diabetes? Have you experienced low blood sugar? If you have T1DM, are using insulin, and have a CGM, you may be able to participate in a research study to see if an oral pill used with your current medications may help to lower the risk of hypoglycemia. Compensation provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Diabetes
Open

Brain Connections in Diabetes

Are you interested in advancing scientific knowledge about diabetes and its impact on brain function? We are currently seeking enthusiastic participants for an exciting research study. This is an excellent opportunity for individuals with type 1 or type 2 diabetes as well as those without diabetes to help us learn how connections in the brain may be different in people with diabetes. Compensation provided.

Age & Gender
  • 25 years ~ 55 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Diabetes
  • Healthy Volunteer or General Population
Not currently enrolling

Diabetes Control in Dialysis-Dependent Kidney Failure

The purpose of this study is to learn if a study medication called semaglutide (known as Ozempic) improves blood sugar control in people treated with dialysis.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
  • Obesity
Open

How does fat impact brain metabolism?

Fuel for Thought: How do sugar and fat affect each other in the brain? Do you ever wonder what happens in your brain when you eat dessert? And why sugary and fatty foods are so appealing? If so, you may eligible to participate in a research study to understand the impact of sugar and fat on the brain!

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Open

How do APOE genetic variants impact brain metabolism?

If you are healthy and between the ages of 18-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Age & Gender
  • 18 years ~ 55 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Open

Type 1 Diabetes Registry

Have you or your child been diagnosed with type 1 diabetes during the past 12 months? Are you interested in helping researchers learn more about how to delay or prevent type 1 diabetes or how to treat type 1 diabetes? Join a registry to be notified of future opportunities to participate in type 1 diabetes research!

Age & Gender
  • 1 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Child and Teen Health
  • Diabetes
  • UNC or UNC Health employees
  • and 3 more
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Rare and Atypical Diabetes Network

This study aims to define new forms of diabetes that are not yet understood. Participants will be asked to provide medical and family history and may be asked to have clinical lab testing performed.

Age & Gender
  • 0 years ~ 80 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Evaluating methods of caring for patients after a recent bone break or fracture

We are launching a national Fracture Prevention Program that aims to improve your bone health and reduce the risk of a future broken bone.

Age & Gender
  • 50 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Bones, Joints, Muscles
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Diabetes Sleep Study

The purpose of this research study is to investigate the relationship between sleep brain wave patterns and peripheral glucose (sugar) levels in individuals with and without type 2 diabetes mellitus (T2DM). Participants will undergo continuous glucose monitoring (CGM) using a CGM device for up to two weeks before an in-laboratory sleep study which is part of routine medical care at UNC to examine how sugar levels fluctuate during sleep and how these fluctuations relate to brain wave activity

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Diabetes
  • Glands and Hormones
  • and 5 more
Visit Location
100% Remote (online, phone, text)
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