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Research Studies

UNC-Chapel Hill Division of Endocrinology and Metabolism

17 studies match your search
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Diabetes Weight Loss Study

Do you have Type 2 Diabetes? Is your BMI in the obesity range and you want to lose weight? You may be eligible to participate in a research study to compare the effectiveness of Tirzepatide vs. a combination drug (Cagrilitide and Semaglutide)

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Obesity
Not currently enrolling

Weight Loss Study

A research study to see how well CagriSema compared to tirzepatide reduces body weight in people with obesity. RECRUITMENT FOR THIS STUDY IS CURRENTLY PAUSED. WE HAVE FILLED ALL AVAILABLE SLOTS AT THIS TIME.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Obesity
Open

Brain Connections in Diabetes

Are you interested in advancing scientific knowledge about diabetes and its impact on brain function? We are currently seeking enthusiastic participants for an exciting research study. This is an excellent opportunity for individuals with type 1 or type 2 diabetes as well as those without diabetes to help us learn how connections in the brain may be different in people with diabetes. Compensation provided.

Age & Gender
  • 25 years ~ 55 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Diabetes
  • Healthy Volunteer or General Population
Open

Type 2 Diabetes Blood Sugar Control and Weight Loss Study

Is your diabetes not well controlled on your current medication(s)? Has your doctor been discussing adding additional medication to help reduce your HbA1c? If you have type 2 diabetes with elevated blood sugars and have excess body weight, you may be able to participate in a research study to find out if an investigational medication can help improve your diabetes and help you lose weight.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Obesity
Open

Diabetes Control in Dialysis-Dependent Kidney Failure

Do you have type 2 diabetes? Do you have kidney failure and require hemodialysis or peritoneal dialysis? You may be able to take part in a research study to find out if using an approved medication (semaglutide) improves blood sugar control. Study medication and diabetes management provided. Participants will be compensated for their time.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
  • Obesity
Open

How does fat impact brain metabolism?

Fuel for Thought: How do sugar and fat affect each other in the brain? Do you ever wonder what happens in your brain when you eat dessert? And why sugary and fatty foods are so appealing? If so, you may eligible to participate in a research study to understand the impact of sugar and fat on the brain!

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Open

How do APOE genetic variants impact brain metabolism?

If you are healthy and between the ages of 30-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Age & Gender
  • 30 years ~ 55 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Not currently enrolling

Type 1 Diabetes Inhaled Insulin Study

In this study, we want to learn more about the safety and effectiveness of inhaled insulin and continuous glucose monitor (CGM) use compared to usual care for people with type 1 diabetes.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
Open

Diabetes Weight Loss Study with Reduction in Hemoglobin A1C

Do you have type 1 diabetes, high blood sugars, and some extra weight to lose? If so, you may be able to take part in a research study to help us learn if an investigational drug could lower blood sugar and help people lose weight. Compensation is provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
Not currently enrolling

Insulin Pump and Continuous Glucose Monitor Study

The study is being done to learn if an insulin pump (the Omnipod 5) can safely adjust insulin for diabetes management in people with type 2 diabetes. The insulin pump is FDA-approved for use with type 1 diabetes, but not yet for type 2 diabetes. We want to learn about its safety and effectiveness compared to insulin injections.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
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