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UNC-Chapel Hill Division of Endocrinology and Metabolism

16 studies match your search
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Diabetes study for patients with diabetes and renal impairment who are currently using basal insulin with or without Metformin or SGLT2 inhibitors

We are seeking participants with type 2 diabetes who use insulin and whose diabetes has affected kidney function and are interested in trying out a new medication that is expected to improve blood sugar control and prevent the weight gain (or induce weight loss) associated with increased insulin use. Compensation for time and travel are provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
Open

Medical Device Removing Excess Tissue in Digestive System in Individuals with Type 2 Diabetes on Insulin Therapy

This is a clinical research study opportunity for people with Type 2 Diabetes using long-acting insulin. In this study, we want to learn more about an innovative approach for improving diabetes outcomes using Fractyl Health's Revita System for removing excess tissue from the small intestine. This minimally invasive procedure is believed to improve blood sugar control and overall metabolic health by altering the body's hormonal response to food intake in a similar way to that achieved with bypass surgery. If you are interested in learning more, please contact us!

Age & Gender
  • 21 years ~ 70 years
  • Male, Female
Study Interest
  • Diabetes
  • Eating, Nutrition, and Metabolism
  • Wellness and Lifestyle
  • UNC or UNC Health employees
Open

Diabetes Weight Loss Study

Do you have Type 2 Diabetes? Is your BMI in the obesity range and you want to lose weight? You may be eligible to participate in a research study to compare the effectiveness of Tirzepatide vs. a combination drug (Cagrilitide and Semaglutide)

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Obesity
Not currently enrolling

Weight Loss Study

A research study to see how well CagriSema compared to tirzepatide reduces body weight in people with obesity. RECRUITMENT FOR THIS STUDY IS CURRENTLY PAUSED. WE HAVE FILLED ALL AVAILABLE SLOTS AT THIS TIME.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Obesity
Open

Brain Connections in Diabetes

Are you interested in advancing scientific knowledge about diabetes and its impact on brain function? We are currently seeking enthusiastic participants for an exciting research study. This is an excellent opportunity for individuals with type 1 or type 2 diabetes as well as those without diabetes to help us learn how connections in the brain may be different in people with diabetes. Compensation provided.

Age & Gender
  • 25 years ~ 55 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Diabetes
  • Healthy Volunteer or General Population
Open

Type 2 Diabetes Blood Sugar Control and Weight Loss Study

Is your diabetes not well controlled on your current medication(s)? Has your doctor been discussing adding additional medication to help reduce your HbA1c? If you have type 2 diabetes with elevated blood sugars and have excess body weight, you may be able to participate in a research study to find out if an investigational medication can help improve your diabetes and help you lose weight.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Obesity
Open

Study for patients who are overweight or obese with heart disease or chronic kidney disease

Are you overweight or obese? If you also have heart disease or kidney disease with at least two risk factors for carviovascular disease, you might be eligible to take part in a research study that may help you reach up to 19% weight loss. In this study, we want to learn if a drug that is being tested is effective in reducing heart disease risks and will help you reach a healthier weight and active lifestyle.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Heart and Circulation
  • Kidneys and Liver
  • Obesity
  • Wellness and Lifestyle
Open

Diabetes Control in Dialysis-Dependent Kidney Failure

Do you have type 2 diabetes? Do you have kidney failure and require hemodialysis or peritoneal dialysis? You may be able to take part in a research study to find out if using an approved medication (semaglutide) improves blood sugar control. Study medication and diabetes management provided. Participants will be compensated for their time.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
  • Obesity
Open

How does fat impact brain metabolism?

Fuel for Thought: How do sugar and fat affect each other in the brain? Do you ever wonder what happens in your brain when you eat dessert? And why sugary and fatty foods are so appealing? If so, you may eligible to participate in a research study to understand the impact of sugar and fat on the brain!

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Open

How do APOE genetic variants impact brain metabolism?

If you are healthy and between the ages of 30-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Age & Gender
  • 30 years ~ 55 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
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