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Research Studies

UNC-Chapel Hill Division of Endocrinology and Metabolism

16 studies match your search
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Type 1 Diabetes Weight Loss Study

The purpose of this study is to look at how safe and effective an investigational medication is for people who have type 1 diabetes and obesity or overweight.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Obesity
Open

How does the way sugar enters the body affect brain glucose?

What factors influence how the brain takes in sugar to use it as energy? If you are between the ages of 18-45 years old and are healthy and of normal weight, you might be eligible to participate in this study to help us understand how the way sugar enters the body affects how sugar enters the brain.

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • and 2 more
Not currently enrolling

Type I Diabetic Insulin Study

The purpose of this study is to find out whether the addition of HDV to Humalog® will improve diabetes control by reducing high blood sugar after meals and/or reducing the risk of low blood sugar (hypoglycemia) during insulin treatment. The safety and tolerability of Humalog® with or without added HDV will also be evaluated. The study drugs will be administered by subcutaneous (under the skin) injection.

Age & Gender
  • 18 years ~ 79 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Kidneys and Liver
Not currently enrolling

Diabetes study for patients with diabetes and renal impairment who are currently using basal insulin with or without Metformin or SGLT2 inhibitors

This study aims to investigate the effectiveness and safety of retatrutide, a new diabetes medication) at doses of 4 mg, 9 mg, or 12 mg that will be taken as a weekly injection for about 1 year, compared to a placebo. A participant's change in HbA1c level will be primary outcome of interest. We are seeking participants with type 2 diabetes that has affected kidney function and are currently taking long-acting insulin with metformin and/or a SGLT2 inhibitor.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
Not currently enrolling

Type One Diabetes and Hypoglycemia Study

This study is looking at how an oral pill used in combination with insulin reduces the risk of low blood sugar.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Diabetes
Not currently enrolling

Improving chronic kidney disease in type 1 diabetes

This is a study for people with chronic kidney disease and type 1 diabetes. In this study, we want to learn more about the effectiveness and safety of a kidney drug called finerenone compared to a placebo.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Kidneys and Liver
  • UNC Students (undergrad, grad, professional)
  • and 2 more
Open

Brain Connections in Diabetes

Are you interested in advancing scientific knowledge about diabetes and its impact on brain function? We are currently seeking enthusiastic participants for an exciting research study. This is an excellent opportunity for individuals with type 1 or type 2 diabetes as well as those without diabetes to help us learn how connections in the brain may be different in people with diabetes. Compensation provided.

Age & Gender
  • 25 years ~ 55 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Diabetes
  • Healthy Volunteer or General Population
Not currently enrolling

Diabetes Control in Dialysis-Dependent Kidney Failure

The purpose of this study is to learn if a study medication called semaglutide (known as Ozempic) improves blood sugar control in people treated with dialysis.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
  • Obesity
Open

How does fat impact brain metabolism?

Fuel for Thought: How do sugar and fat affect each other in the brain? Do you ever wonder what happens in your brain when you eat dessert? And why sugary and fatty foods are so appealing? If so, you may eligible to participate in a research study to understand the impact of sugar and fat on the brain!

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Open

How do APOE genetic variants impact brain metabolism?

If you are healthy and between the ages of 18-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Age & Gender
  • 18 years ~ 55 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
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