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Research Studies

UNC-Chapel Hill Division of Endocrinology and Metabolism

17 studies match your search
Not currently enrolling

Type I Diabetic Insulin Study

The purpose of this study is to find out whether the addition of HDV to Humalog® will improve diabetes control by reducing high blood sugar after meals and/or reducing the risk of low blood sugar (hypoglycemia) during insulin treatment. The safety and tolerability of Humalog® with or without added HDV will also be evaluated. The study drugs will be administered by subcutaneous (under the skin) injection.

Age & Gender
  • 18 years ~ 79 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Kidneys and Liver
Open

Type 2 Diabetes Blood Sugar Control and Weight Loss Study

Do you have type 2 diabetes? Do you take insulin once daily alone or in combination with metformin? If you want to help the development of future type 2 diabetes treatment, then this clinical study may be for you.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
Open

Diabetes study for patients with diabetes and renal impairment who are currently using basal insulin with or without Metformin or SGLT2 inhibitors

We are seeking participants with type 2 diabetes who use insulin and whose diabetes has affected kidney function and are interested in trying out a new medication that is expected to improve blood sugar control and prevent the weight gain (or induce weight loss) associated with increased insulin use. Compensation for time and travel are provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
Open

Diabetes Weight Loss Study

Do you have Type 2 Diabetes? Is your BMI in the obesity range and you want to lose weight? You may be eligible to participate in a research study to compare the effectiveness of Tirzepatide vs. a combination drug (Cagrilitide and Semaglutide)

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Obesity
Open

Improving chronic kidney disease in type 1 diabetes

Do you have Type 1 Diabetes and Chronic Kidney Disease as a result of your diabetes? Do you want stop or slow the progression of your kidney disease? If so, you may be able to take part in the FINE-ONE study to learn more about a kidney drug called finerenone. Compensation is provided for participation.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Kidneys and Liver
  • UNC Students (undergrad, grad, professional)
  • and 2 more
Not currently enrolling

Weight Loss Study

A research study to see how well CagriSema compared to tirzepatide reduces body weight in people with obesity. RECRUITMENT FOR THIS STUDY IS CURRENTLY PAUSED. WE HAVE FILLED ALL AVAILABLE SLOTS AT THIS TIME.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Obesity
Open

Brain Connections in Diabetes

Are you interested in advancing scientific knowledge about diabetes and its impact on brain function? We are currently seeking enthusiastic participants for an exciting research study. This is an excellent opportunity for individuals with type 1 or type 2 diabetes as well as those without diabetes to help us learn how connections in the brain may be different in people with diabetes. Compensation provided.

Age & Gender
  • 25 years ~ 55 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Diabetes
  • Healthy Volunteer or General Population
Not currently enrolling

Type 2 Diabetes Blood Sugar Control and Weight Loss Study

A research study to see how well CagriSema compared to semaglutide, cagrilintide and placebo lowers blood sugar and body weight in people with type 2 diabetes treated with metformin with or without an SGLT2 inhibitor

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Obesity
Open

Study for patients who are overweight or obese with heart disease or chronic kidney disease

Are you overweight or obese? If you also have heart disease or kidney disease with at least two risk factors for carviovascular disease, you might be eligible to take part in a research study that may help you reach up to 19% weight loss. In this study, we want to learn if a drug that is being tested is effective in reducing heart disease risks and will help you reach a healthier weight and active lifestyle.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Heart and Circulation
  • Kidneys and Liver
  • Obesity
  • Wellness and Lifestyle
Open

Diabetes Control in Dialysis-Dependent Kidney Failure

Do you have type 2 diabetes? Do you have kidney failure and require hemodialysis or peritoneal dialysis? You may be able to take part in a research study to find out if using an approved medication (semaglutide) improves blood sugar control. Study medication and diabetes management provided. Participants will be compensated for their time.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
  • Obesity
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