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Research Studies

UNC-Chapel Hill Division of Endocrinology and Metabolism

17 studies match your search
Open

How does the way sugar enters the body affect brain glucose?

What factors influence how the brain takes in sugar to use it as energy? If you are between the ages of 18-45 years old and are healthy and of normal weight, you might be eligible to participate in this study to help us understand how the way sugar enters the body affects how sugar enters the brain.

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • and 2 more
Open

Type 2 Diabetes Blood Sugar Control and Weight Loss Study

Do you have type 2 diabetes? Do you take insulin once daily alone or in combination with metformin? If you want to help the development of future type 2 diabetes treatment, then this clinical study may be for you.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
Open

Diabetes study for patients with diabetes and renal impairment who are currently using basal insulin with or without Metformin or SGLT2 inhibitors

We are seeking participants with type 2 diabetes who use insulin and whose diabetes has affected kidney function and are interested in trying out a new medication that is expected to improve blood sugar control and prevent the weight gain (or induce weight loss) associated with increased insulin use. Compensation for time and travel are provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
Open

Type One Diabetes and Hypoglycemia Study

Do you have type one diabetes? Have you experienced low blood sugar? If you have T1DM, are using insulin, and have a CGM, you may be able to participate in a research study to see if an oral pill used with your current medications may help to lower the risk of hypoglycemia. Compensation provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Diabetes
Open

Improving chronic kidney disease in type 1 diabetes

Do you have Type 1 Diabetes and Chronic Kidney Disease as a result of your diabetes? Do you want stop or slow the progression of your kidney disease? If so, you may be able to take part in the FINE-ONE study to learn more about a kidney drug called finerenone. Compensation is provided for participation.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Kidneys and Liver
  • UNC Students (undergrad, grad, professional)
  • and 2 more
Open

Brain Connections in Diabetes

Are you interested in advancing scientific knowledge about diabetes and its impact on brain function? We are currently seeking enthusiastic participants for an exciting research study. This is an excellent opportunity for individuals with type 1 or type 2 diabetes as well as those without diabetes to help us learn how connections in the brain may be different in people with diabetes. Compensation provided.

Age & Gender
  • 25 years ~ 55 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Diabetes
  • Healthy Volunteer or General Population
Open

Study for patients who are overweight or obese with heart disease or chronic kidney disease

Are you overweight or obese? If you also have heart disease or kidney disease with at least two risk factors for carviovascular disease, you might be eligible to take part in a research study that may help you reach up to 19% weight loss. In this study, we want to learn if a drug that is being tested is effective in reducing heart disease risks and will help you reach a healthier weight and active lifestyle.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Heart and Circulation
  • Kidneys and Liver
  • Obesity
  • Wellness and Lifestyle
Not currently enrolling

Diabetes Control in Dialysis-Dependent Kidney Failure

The purpose of this study is to learn if a study medication called semaglutide (known as Ozempic) improves blood sugar control in people treated with dialysis.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
  • Obesity
Open

How does fat impact brain metabolism?

Fuel for Thought: How do sugar and fat affect each other in the brain? Do you ever wonder what happens in your brain when you eat dessert? And why sugary and fatty foods are so appealing? If so, you may eligible to participate in a research study to understand the impact of sugar and fat on the brain!

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Open

How do APOE genetic variants impact brain metabolism?

If you are healthy and between the ages of 18-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Age & Gender
  • 18 years ~ 55 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
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