The purpose of this study is to compare the usual treatment alone (chemoradiation and pembrolizumab followed by pembrolizumab) to using induction chemotherapy therapy with pembrolizumab before chemoradiation and pembrolizumab followed by pembrolizumab. The addition of providing induction therapy (carboplatin, paclitaxel, and pembrolizumab) prior to the usual chemoradiation and pembrolizumab therapy could shrink your cancer or prevent it from returning

This study is about understanding how the culture of celebrities losing weight can impact how plus-size individuals understand body-related movements such as body positivity and fat acceptance, along with how they navigate their own body image. We would like to center the voices of people whose bodies are most often discussed, but least often heard in conversations around weight loss, celebrity culture, and body image to understand how these messages affect mental health and everyday experiences.

This study looks into how Black adults feel about their health care. We want to know how they decide to go to the doctor or get check-ups. Some may feel ignored, not heard, or confused by medical advice, which can affect their willingness to see a doctor or follow advice. By talking with you, we aim to understand what challenges you face in health care and how these affect your health decisions. Our goal is to learn from your experience so that doctors and communities can make preventive care better and more trustworthy for everyone.

Have you welcomed a baby in the last year and felt symptoms of depression during pregnancy or after birth? We're inviting Latina mothers to talk about their experiences with getting care and support during this time. By joining a one-time, private video chat, you can help researchers learn what makes it easier or harder for mothers like you to access depression care. Your insights could help improve future support and care for Latina mothers. Plus, you'll receive a $40 gift card to thank you for your time.

Struggling to control your type 2 diabetes? You may be able to participate in a research study to find out if you have elevated cortisol levels - a hidden factor that could be making blood sugar harder to manage - and if so, you may receive a study treatment that could help reduce the effects of excess cortisol.

Do you suffer from chronic pain? If you have been treated for chronic non-cancer pain at a clinic or hospital in the Piedmont Triad or Triangle within the last year, you may be able to participate in a research study that examines people's experiences with chronic pain treatment. Compensation provided.

We're looking into how students with different ways of thinking, known as neurodivergent students, see the pros and cons of using AI chatbots. It's crucial that these students, who know from personal experience, are the ones creating these guidelines.

Do you have hereditary transthyretin amyloidosis (hATTR) with polyneuropathy? If so, you could be involved in a clinical trial to test the safety of a new investigational drug for this disease.

You can help us change the way we treat overactive bladder. Right now, 60 million people in the U.S. deal with this condition, and treatments don't work the same for everyone. We think mental health, mood, and sleep might play a role, and we need your help to figure it out! All you need to do is answer some quick questions about your bladder, mood, and sleep before treatment starts and once more 2-4 months later. Your input could show us how improving mental well-being could make overactive bladder treatments work better.

Do you have Crohn's disease and painful period cramps? You may be able to join a research study. We want to learn which pain medicine works best and is safest for people with Crohn's disease.