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Older Adult (65+)
2142 studies match your search

Dara-RVd Induction for newly diagnosed multiple myeloma with autologous stem cell transplantation

In this study, we want to see what happens when one of the drugs in a 4-drug combination called Dara-RVd is given once a week instead of twice a week. We will look at how this timing change affects the outcome of multiple myeloma with autologous stem cell transplantation. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Multiple Myeloma)
Not currently enrolling

Dose-escalation and expansion study of BAY 3375968 (anti-CCR8 antibody) as monotherapy and in combination with pembrolizumab in selected advanced solid tumors

This study will evaluate BAY 3375968 as a new immunotherapeutic agent in advanced solid tumor settings of high medical need.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder, Breast, Colorectal, and 5 more)
Open

Liver Cancer Screening Study

If you have liver cirrhosis or chronic hepatitis B infection, you may qualify to participate in a research study that compares the effectiveness of two liver cancer screening methods. Please contact the study team to get more information. Compensation provided.

Age & Gender
  • 18 years ~ 85 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Open

PRevention Of Frailty with Fisetin (PROFFi) in Breast Cancer Survivors

Are you a breast cancer survivor? if soy you may be eligible to participate in this research study that is looking at the effectiveness of fisetin and/or exercise on physical function assessed using a 6 minute walking distance in chemotherapy-treated postmenopausal breast cancer survivors

Age & Gender
  • 18 years ~ 70 years
  • Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Not currently enrolling

Akero 106

We are studying an investigational drug, Efruxifermin, to see if it will help in the treatment of liver inflammation and scarring (fibrosis) in adults diagnosed with Compensated Cirrhosis due to NASH (non-alcoholic steatohepatitis) and MASH (metabolic dysfunction-associated steatohepatitis).

Age & Gender
  • 18 years ~ 80 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Open

An Open-Label, Multicenter, First-in-Human, Dose-Escalation, Multicohort, Phase 1/2 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

Do you have With Locally Advanced or Metastatic Solid Tumors of the Head or Neck? If so, you may be able to participate in a research study to to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of INBRX 106 administered as a single agent or in combination with the anti-PD-1 checkpoint inhibitor (CPI) pembrolizumab (Keytruda®).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)
Open

EFFICACY AND SAFETY OF DIVARASIB VERSUS SOTORASIB OR ADAGRASIB IN PATIENTS WITH NON-SMALL CELL LUNG CANCER

Do you have non small cell lung cancer? Are you currently not on any other treatments for your cancer? If you answered yes, you may be able to take part in a lung cancer medication study.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Not currently enrolling

Metastatic Non-small Cell Lung Cancer Treatment

In this study, we want to see how patients with metastatic non-small cell lung cancer do with two treatments: ivonescimab and chemotherapy. We are comparing these treatments to find out which one helps patients more.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Not currently enrolling

Web Application Study

In this study, we want to test a new web application we are creating. The app will help users find important information about digital health resources and how ready a community is to use them.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Environment
  • Healthy Volunteer or General Population
  • Wellness and Lifestyle
  • UNC or UNC Health employees
Visit Location
100% Remote (online, phone, text)
Not currently enrolling

PREserving Valued Activities In Life

To conduct a pilot trial to determine feasibility and acceptability of the refined PREVAIL model in at least 50 adults with rheumatoid arthritis.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Pain
  • Movement
Visit Location
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