Have you diagnosed with lymph node positive early breast cancer, have received surgery, and have not received any systemic or radiation treatment prior to surgery? If so, you may be able to take part in this clinical trial which seeks to improve the treatment of early-stage breast cancer by examining ctDNA, a biomarker found in the blood that may indicate the presence of disease. This study aims to determine if ctDNA can help doctors personalize therapies leading to more effective treatment plans.

Do you have acid reflux, GERD, or Barrett's Esophagus? Are you having standard of care endoscopies performed? You may be able to participate in a research study testing for Barrett's Esophagus and esophageal cancer. Compensation provided.

Are you currently using insulin to treat type 2 diabetes? Are your blood sugar values still not where your provider wants them to be? If you are willing to use an automated insulin delivery system, involving an insulin pump and a continuous glucose monitor, you may be eligible to participate in a research study to find out if the twiist system can improve glycemic control.

Have you been diagnosed with Leukemia? Do you have a functioning kidney, liver, and cardiac organ? If so, you may be able to participate in a study on a new drug called LBS-007. We want to find out if it is safe for people with Leukemia. Compensation provided.

Have you been diganosed with epithelial high grade ovarian, fallopian tube or primary peritoneal carcinoma? if so, you may be able to participate in this research study to evaluate if the combination of Trastuzumab Deruxtecan (T-DXd) and Bevacizumab works better than bevacizumab alone for the treatment of your type of cancer.

Do you or your child have alopecia areata? Would you be interested in hearing more about a clinical study on alopecia areata? If so, you may be able to participate in a research study to find out how effective and safe the study medication ritlecitinib is in patients with alopecia areata.

Preventing walking disability in our rapidly aging population is an enormous public health challenge. Fundamental to their loss of functional mobility is that the muscles needed to power walking experience decline in function with age. Wearable assistive devices can be designed to augment the function of these muscles and may make walking easier. If you are a healthy older adult, you may be able to participate in a training intervention to determine the feasibility of a passive wearable ankle device that strengthens walking dynamics and decreases fall risk.

Most patients with generalized Myasthenia Gravis need treatments that carry substantial risk of side effects and toxicity, Descartes-08 is a cell therapy is a RNA based CAR-T that causes direct killing of target cells without serious generalized toxicities.

We are looking at how parents and adolescents in 5th or 6th grade use social media and how this use relates to body image and mental health. We are interested in this because of the high rates of social media use among adolescents, and the concerns the general public has about how use relates to mental health.

The purpose of this study is to determine the efficacy and safety of an investigational oral medication compared with placebo in people with obesity or overweight with and without type 2 diabetes