This is a multicenter, open-label study to study the safety and characteristics of DNL310, an investigational drug designed to treat both the body and brain manifestations of Mucopolysaccharidosis type II (MPS II; Hunter syndrome). The plan is for each participant to start at a low dose and increase over time until a final dose is achieved. Blood, urine and CSF samples will be taken, and tests and assessments will be done to see how your child is doing in the study.
The purpose of this study is to assess the impacts and perceived benefits of the HPPTS program. Community college students transferring to UNC through the C-STEP program will be invited to apply and if accepted, invited to participate in the study that will involve submission of questionnaires and participation in focus groups.
The purpose of this study is to understand what individuals focus on at work and how that influences their perceptions and behavior.
After conducting a thorough literature review to capture all current areas of care and treatment for MPS II patients, a brief overview of the literature was presented to a group of MPS experts, including the principal investigator and co-investigators. From this overview, the Delphi statements were created. The Delphi statements were then put into Qualtrics to create a survey. The survey will be sent to practitioners who care for and treat MPS II patients, including MDs, PhDs, APPs, or those holding an advanced degree in a relevant field. Participants will be asked to answer a few demographic questions to see if they qualify for the survey. From the survey, we will determine a level of agreement and publish the results in a medical journal
This study focuses on relationships between clinical service providers and young autistic children between the ages of 3 and 6. We want to understand what individual characteristics and behaviors influence connection and cooperation between children and their clinicians.
The purpose of this study is to learn what women with HIV think about cervical cancer screening. We also want to talk about the idea of using HPV self-collection (where women collect their own sample) instead of going to the clinic for testing. This information will help us see if self- collection can help more women with HIV get screened for cervical cancer.
We are conducting a research study to explore the limitations of working memory load on initial attention capture and the precise timing of subsequent hold. In our foundational framework, we are incorporating a diverse range of stimuli to comprehensively capture attention and evaluate hold across two different attention paradigms.
Study to evaluate the safety and effectiveness of the InnAVasc Arteriovenous Graft (IG) for hemodialysis (HD) access in patients with end-stage renal disease (ESRD).
This study will be conducted in order to explore how children acquire and use emotion words and concepts by looking at syntactic structure and visual influence.
The study explores imposter syndrome in EXSS undergraduates and factors associated with it.