The primary objective of PATIENCE is to develop a standardized approach to the treatment of NTM in CF patients with a diagnosis of NTM disease. The secondary objectives are to: - Evaluate the feasibility and tolerability of a standardized treatment protocol for NTM disease - Evaluate effectiveness of a standardized NTM disease treatment protocol to serve as baseline/reference estimates of endpoints in clinical care and future therapeutic trials - Support biomarker development for markers of NTM treatment response through banking of clinical specimens and NTM isolates linked with outcomes data - Characterize clinical features of patients achieving treatment success compared to those unresponsive to treatment
To follow people with cystic fibrosis who have cultured a positive NTM bacteria.
Emergency medical services provide prehospital emergency care across North Carolina, and often provide care to patients struggling with opioids. Care provided to these patients may be in the form of prevention, treatments, and harm reduction strategies. This study intends to gather information using a survey sent out to EMS administrators in NC, to ask questions about the prehospital treatment of patients with opioid use disorder. The survey will include questions about the number of patients they see and the strategies they use to treat these patients.
The purpose of this study is to explore the home shared reading resources and experiences of Mandarin-speaking children who cannot rely on speech to be heard and understood in Taiwan, as reported by their parents through questionnaires. This data will also be compared with an existing national survey of 11,551 parents of children without disabilities in Taiwan.
Ovarian cancer is the second most frequently diagnosed gynecologic cancer in the United States. Although it is the eleventh most common cancer among women, ovarian cancer is the fifth leading cause of cancer-related death. Fortunately, survival rates for ovarian cancer patients have been improving over the past few decades due to advances in medical procedures and the availability of new cancer drugs. However, studies have shown that the improvement of clinical outcomes are unequal among patients of different racial and ethnic backgrounds. This study seeks to understand the factors associated with healthcare disparities in Black ovarian cancer patients and identify features of programs that have been successful in addressing these racial imbalances. The findings of this study will help the researcher develop future programs to address healthcare disparities in Black ovarian cancer patients.
The purpose of this study is to assess how the use of community health-workers for human papillomavirus (HPV) testing influences the number of women living with HIV who get screened for cervical cancer.
This study will help us learn more about how strongly our Triple P professional networks, both individual and organizational, in North Carolina and South Carolina are connected. We'll use this information to help create or sustain network connections to promote effective implementation of the Triple P Positive Parenting Program.
The sponsor is doing this study because they want to learn certain things about the study drug Lenacapavir (LEN), including: • How LEN moves through the body. • How safe and tolerable LEN is when injected into the muscle once yearly.
The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Crohn's disease.
The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Ulcerative Colitis.