To evaluate the safety and tolerability of ALX148 in combination with enfortumab vedotin in subjects with previously treated locally advanced or metastatic urothelial carcinoma. To determine the maximum tolerated dose (MTD) and the recommended Phase 2 dose (RP2D) of ALX148 in combination with enfortumab vedotin.

The expected outcome of this proposal is a novel care pathway delivered by pharmacists to improve side effects during oral chemotherapy for patients, a known barrier to adherence, and ultimately to prevent progression and early mortality. Our long-term goal for P3OC is to develop and test new dashboard features to optimize pharmacy care, meet future needs for value-based payment models, and improve patient outcomes.

To assess interest in and barrier to implementation of Age-Based Genomic Screening within North Carolina Network Consortium-member clinics.

We are adapting a universal mindfulness-based social-emotional learning program for delivery by middle school counselors to students with high levels of stress.

We are evaluating the reliability of a new survey on food addiction, and exploring questions on eco-anxiety. We will also assess characteristics of and associations between food addiction, eco-anxiety, impulsivity, disordered eating, and depression. Information collected from this study will provide data for larger foundation or NIH grants.

The purpose of this study is to examine how resting brain activity is related to sleep behaviors and reactions to drinking alcohol.

Research will be done to compare accessibility between a public and an academic library.

The purpose of this study is to collect data related to patient reported outcomes (pain, function, quality of life, toxicity) with the goal of managing approaches to radiation therapy and clinical care during follow up.

This study aims to evaluate the usability of the symptom monitoring tool and understand the barriers to completing symptom assessments among patients with chest surgery. Using a symptom monitoring tool, patients will directly report their symptoms to their care team by completing electronic patient-reported outcome (ePRO) assessments.

We are interested in better understanding the experiences of a diverse group of individuals of South Asian descent with their body image and eating patterns, including what factors are associated with body dissatisfaction and disordered eating and which factors may be protective.