The aim of this study is to measure the efficacy (how well it works) and safety of efgartigimod compared with placebo (inactive substance) in participants with ocular myasthenia gravis (oMG). The study will also measure the long-term efficacy, safety, and tolerability of efgartigimod.
This research is being done in participants who have Hepatocellular Carcinoma (HCC), also referred to as Liver Cancer, to evaluate how 3 drugs work in combination, and which dose is the best to treat your disease. The 3 drugs are casdozokitug (casdozo-key-tug), toripalimab (tor-i-pal-i- mab) and bevacizumab (bev-uh-siz-oo-mab). Toripalimab and bevacizumab have been approved by the Food and Drug Administration (FDA) to treat other cancers, but not Liver cancer. Casdozokitug has not been approved by the FDA to treat any cancers.
Have you been diagnosed with advanced breast, lung, colorectal, or bladder cancer and does your doctor plan to send a sample of your tumor for genetic testing? If so, then you may be able to take part in a research study that looks at whether an expert review of your tumor genetic test results can help your doctor identify better treatment options or clinical trials that may be suitable for your cancer.
Are you right-handed? Are you between the ages 18 and 35 or 65 and 85? Are you interested in testing your memory? If so, you may be able to take part in a study on how younger and older adults learn and remember objects. You can help us learn more about how memory works in adults! Compensation provided.
The purpose of this research is to see if an experimental vaccine, which is created from your tumor tissue and dendritic cells isolated from your blood, can be an effective therapy when given after your standard treatment of surgery, chemotherapy, and radiation.
Have you been diagnosed with anaplastic thyroid cancer? If so, you might be able to take part in a study to look at the effectiveness of taking cemiplimab and XL092 before and after surgery for your cancer.
Have you been diagnosed with Lupus or Lupus Nephritis? A single infusion of CD19-directed CAR T therapy may help reset your immune system by targeting harmful B cells, potentially leading to long-term disease control without ongoing treatment.
Did you recently have an ACLR? Are you aware of your increase chances of developing knee osteoarthritis? If so, please participate in our study analyzing how knee joint movements are linked to cartilage strain to help prevent knee osteoarthritis. Compensation provided.
In this study, we want to find out if a single therapy session that shows people how to deal with depression is effective.
By doing this study, we hope to learn if the combination of belantamab mafodotin, carfilzomib, pomalidomide, and dexamethasone is effective and safe when given to persons with multiple myeloma that has gotten worse and is not responding to standard drugs that are used for treating multiple myeloma, including chimeric antigen receptor T-cell therapy.