Is your child between the ages of 8 and 11? Was your child assigned female sex at birth? If so, you may be able to take part in a study to see how social experiences and puberty can affect the mental health of preteen girls. We want to help improve youth mental health support. Compensation provided.

Do you have solid tumor of the lung or esophagus? Have the standard treatments for your condition been ineffective or not tolerable? If so, you may be eligible to participate in an early phase research study of the investigational drug YL201 as a possible treatment for advanced solid tumors.

This research is being done in participants who have Hepatocellular Carcinoma (HCC), also referred to as Liver Cancer, to evaluate how 3 drugs work in combination, and which dose is the best to treat your disease. The 3 drugs are casdozokitug (casdozo-key-tug), toripalimab (tor-i-pal-i- mab) and bevacizumab (bev-uh-siz-oo-mab). Toripalimab and bevacizumab have been approved by the Food and Drug Administration (FDA) to treat other cancers, but not Liver cancer. Casdozokitug has not been approved by the FDA to treat any cancers.

This study is assessing the usefulness of a text message based intervention to reduce excessive alcohol use among young adults ages 18-25. Participants will attend a Baseline Session over Zoom where they will complete a 25-minute survey and learn more about study procedures. Then, participants will receive daily prompts to their personal cellphone Wednesday-Sunday for 4 weeks. After the 4-week trial, participants will attend 1 focus group over Zoom to share their experiences in the study.

Are you right-handed? Are you between the ages 18 and 35 or 65 and 85? Are you interested in testing your memory? If so, you may be able to take part in a study on how younger and older adults learn and remember objects. You can help us learn more about how memory works in adults! Compensation provided.

The purpose of this research is to see if an experimental vaccine, which is created from your tumor tissue and dendritic cells isolated from your blood, can be an effective therapy when given after your standard treatment of surgery, chemotherapy, and radiation.

Have you been diagnosed with anaplastic thyroid cancer? If so, you might be able to take part in a study to look at the effectiveness of taking cemiplimab and XL092 before and after surgery for your cancer.

Have you been diagnosed with Lupus or Lupus Nephritis? A single infusion of CD19-directed CAR T therapy may help reset your immune system by targeting harmful B cells, potentially leading to long-term disease control without ongoing treatment.

Did you recently have an ACLR? Are you aware of your increase chances of developing knee osteoarthritis? If so, please participate in our study analyzing how knee joint movements are linked to cartilage strain to help prevent knee osteoarthritis. Compensation provided.

In this study, we want to find out if a single therapy session that shows people how to deal with depression is effective.