This study is being carried out to learn more about administration of xaluritamig in people with high-risk biochemical recurrence (BCR) or sometimes referred to as nonmetastatic castration-sensitive prostate cancer (nmCSPC) after receiving definitive (primary) treatment.

Are you interested in how daily health behaviors impact inflammation? Are you a non-drinker OR do you regularly drink alcohol? If so, you may be able to participate in a research study to find out how daily alcohol use relates to inflammation. Those with a history of alcohol use disorder are welcome as well! Compensation provided.

Do you have early-stage endometrial cancer? If so, you may be able to take part in a research study looking to find out if there are types of early-stage endometrial cancer that require less treatment than the usual approac

The purpose of this study is to study the relationship between alcohol consumption history and immune responses. We are examining whether people with different drinking histories have different patterns of immune reactivity, based on blood measurements. Participants will be asked to attend one visit to UNC for a blood sample and questionnaires. Total time of participation is estimated at 2-3 hours.

Do you struggle with ways to feel more relaxed or calm when you are stressed? Do you identify as African American, Black, Hispanic, and/or Latino (a/e/x)? If so, you may be able to take part in a study to see whether a home-based training program can improve emotional well-being and heart health. Compensation provided.

The purpose of this study is to understand how much people know about skin cancer and how they protect their skin. We are looking at people's knowledge about different types of skin cancer and their behaviors to prevent it. We want to see if there are common habits or barriers that affect how people take care of their skin. By learning more about these things, we hope to improve ways to promote skin health and prevent skin cancer.

Do you have advanced melanoma that has progressed on treatment? Do you have a tumor longer than 1cm in length? If so, you might be able to take part in a study that compares a study treatment (Vusolimogene Oderparepvec and Nivolumab) with your physician's choice of standard of care treatment. Compensation provided.

Have you been diagnosed with hormone receptor (HR+) and human epidermal growth factor receptor 2 (HER2)-negative recurrent or metastatic breast cancer? If so, you may be eligible for a clinical trial investigating the combination of endocrine therapy with alisertib.

Have you been diagnosed with cancer. If so, you may be able to take part in a research study looking to improve cancer care for patients whose treatment outcomes have led to challenges in their quality of life.

Does hypertonic saline improve mucus clearance in bronchiectasis? The purpose of this research study is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lungs in people with bronchiectasis. We will compare mucociliary clearance (MCC: a measurement of the rate at which a person's lungs can clear inhaled particles) at baseline, after a single dose of HS, and after two weeks of treatment with HS twice a day. We will also assess response to HS with other outcomes (spirometry, multiple breath washout [MBW], changes in sputum [coughed up mucus or phlegm], and survey responses). Compensation provided. No blood draws required.