Have you been diagnosed with Leukemia? Do you have a functioning kidney, liver, and cardiac organ? If so, you may be able to participate in a study on a new drug called LBS-007. We want to find out if it is safe for people with Leukemia. Compensation provided.

Have you diagnosed with lymph node positive early breast cancer, have received surgery, and have not received any systemic or radiation treatment prior to surgery? If so, you may be able to take part in this clinical trial which seeks to improve the treatment of early-stage breast cancer by examining ctDNA, a biomarker found in the blood that may indicate the presence of disease. This study aims to determine if ctDNA can help doctors personalize therapies leading to more effective treatment plans.

Do you have acid reflux, GERD, or Barrett's Esophagus? Are you having standard of care endoscopies performed? You may be able to participate in a research study testing for Barrett's Esophagus and esophageal cancer. Compensation provided.

Have you been diganosed with epithelial high grade ovarian, fallopian tube or primary peritoneal carcinoma? if so, you may be able to participate in this research study to evaluate if the combination of Trastuzumab Deruxtecan (T-DXd) and Bevacizumab works better than bevacizumab alone for the treatment of your type of cancer.

Big Discoveries Start Small! Looking for Young Explorers to Join Our Screen Time Study Have a child ages 3-8? Spectra Discovery is a one-week research study exploring how wearable devices might track screen time in young children. Your child will wear fake glasses, a shirt clip, and a belt activity counter while using a study-provided tablet. Parents will complete brief daily surveys and device logs. Orientation can happen at home or at our Chapel Hill office. Parents are compensated, and kids receive a special thank-you gift! Help us better understand screen use in children-click to learn more.

Do you or your child have alopecia areata? Would you be interested in hearing more about a clinical study on alopecia areata? If so, you may be able to participate in a research study to find out how effective and safe the study medication ritlecitinib is in patients with alopecia areata.

Preventing walking disability in our rapidly aging population is an enormous public health challenge. Fundamental to their loss of functional mobility is that the muscles needed to power walking experience decline in function with age. Wearable assistive devices can be designed to augment the function of these muscles and may make walking easier. If you are a healthy older adult, you may be able to participate in a training intervention to determine the feasibility of a passive wearable ankle device that strengthens walking dynamics and decreases fall risk.

Most patients with generalized Myasthenia Gravis need treatments that carry substantial risk of side effects and toxicity, Descartes-08 is a cell therapy is a RNA based CAR-T that causes direct killing of target cells without serious generalized toxicities.

Do you have chronic limb-threatening ischemia? This might cause you pain, slow-healing wounds, or make it hard to decide about surgeries and treatments for your leg or foot. We want to hear from you. What has getting the care you need been like? Have you ever felt unsure about your treatment options or needed more support? Sharing your story can help us make care better for others with the same condition. It might help doctors to explain things more clearly, find better ways to manage pain, or support people who worry about their independence. We will talk with you two times-now and again in six months-to hear about your experiences. Your story can help make care easier and better for people in the future.

Have you had a stillborn baby or delivered a baby before 35 weeks? You might be able to join the ADEPT study. These situations can make your current pregnancy higher risk. Doctors often suggest taking aspirin to help. This study wants to find out if taking a higher dose of aspirin works better to lower the risk of having another preterm delivery or stillborn baby.