Most patients with generalized Myasthenia Gravis need treatments that carry substantial risk of side effects and toxicity, Descartes-08 is a cell therapy is a RNA based CAR-T that causes direct killing of target cells without serious generalized toxicities.

Do you have chronic limb-threatening ischemia? This might cause you pain, slow-healing wounds, or make it hard to decide about surgeries and treatments for your leg or foot. We want to hear from you. What has getting the care you need been like? Have you ever felt unsure about your treatment options or needed more support? Sharing your story can help us make care better for others with the same condition. It might help doctors to explain things more clearly, find better ways to manage pain, or support people who worry about their independence. We will talk with you two times-now and again in six months-to hear about your experiences. Your story can help make care easier and better for people in the future.

Have you had a stillborn baby or delivered a baby before 35 weeks? You might be able to join the ADEPT study. These situations can make your current pregnancy higher risk. Doctors often suggest taking aspirin to help. This study wants to find out if taking a higher dose of aspirin works better to lower the risk of having another preterm delivery or stillborn baby.

Have you been diagnosed with Metastatic Colorectal Cancer? If so, you might be able to take part in a study to see if an investigational product is safe and effective for treating metastatic colorectal cancer.

We are looking for people who are between the ages of 1 and 55 years who have food allergies to two or more of the following foods: peanut, cashew, walnut, egg, or milk

Do you have type 1 diabetes? Has your doctor told you that your HbA1c is higher than the goal? Do you also have excess body weight? If you are having a hard time controlling your blood sugar with only insulin, you may be able to participate in a research study to see if taking an investigational medication once weekly can help improve your blood sugar control and reduce your body weight.

Have you had an alcoholic drink today or in the past 4 months? Have you been diagnosed with alcohol-related liver disease (ALD)? You may be able to participate in a research study that is exploring a medication that may help reduce the effects of ALD. Compensation provided.

We want to hear from you! If you are a college student, please take our quick survey. It will take about 15 minutes. We want to know how you feel about being part of our campus. Your answers are private. You can also enter to win a $20 Amazon gift card. We have 50 gift cards to give away! You don't have to do the survey to enter the raffle.

Feel anxious when your body goes into "fight or flight?" You may be eligible to participate in a research study to learn how difficult emotions, such as anxiety and fear, relate to feelings in the body. Compensation provided.

Has your partner ever used a gun to hurt or scare you? Have you ever filed for a protective order in North Carolina? If so, we'd like to talk to you about your experiences. Click the link to find out if you qualify for a research study about domestic violence protective orders and guns. Participation includes a phone interview and compensation is provided.