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UNC-Chapel Hill Lineberger Comprehensive Cancer Center

266 studies match your search
Open

MB-105 in Patients with CD5 Positive Relapsed/Refractory T-Cell Lymphoma

Do you have T-cell Lymphoma? Is your disease relapsed or refractory and CD5 positive? If so, you may be able to participate in this gene therapy research study to learn more about using your own modified immune cells as possible treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lymphoma)
Open

Petosemtamab Drug Study

Do you have incurable, metastatic/recurrent head and neck squamous cell carcinoma? If so, you may be able to take part in a study to see if a new drug called petosemtamab is effective. We want to see if petosemtamab works better than the treatments doctors usually use for head and neck squamous cell carcinoma. Compensation provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)
Open

Study of RP1 in Organ and Cell Transplant Patients With Skin Cancer

Have you had an organ transplant or hematopoietic cell transplant and have advanced cutaneous squamous cell carcinoma? If so, you might be eligible to take part in a study to see if an investigation drug, RP1, can help treat your skin cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Other Cancers)
Not currently enrolling

Radiation-Induced Xerostomia Long-Term Follow-Up Study

In this study, we want to asses the long-term safety of using a virus to deliver a gene, AAV2-hAQP1, and how effective this gene is at treating dry mouth in people who have received radiation therapy for head and neck cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)

Dara-RVd Induction for newly diagnosed multiple myeloma with autologous stem cell transplantation

In this study, we want to see what happens when one of the drugs in a 4-drug combination called Dara-RVd is given once a week instead of twice a week. We will look at how this timing change affects the outcome of multiple myeloma with autologous stem cell transplantation. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Multiple Myeloma)
Open

Study for Patients with Non-small Cell Lung Cancer

Have you been diagnosed with Stage III non-small cell lung cancer? Is your cancer advanced and not able to to removed? If so, you might be able to participate in a study that looks at a study drug to see if it can help the radiation treatment work better against your cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
Open

A study to compare two surgical procedures in individuals with BRCA1 mutations to assess reduced risk of ovarian cancer

Do you have BRCA1 mutation and have elected to undergo a surgical intervention? If so, you may be able to take part in a research study comparing two surgical procedures and their ability to decrease the risk of developing ovarian cancer.

Age & Gender
  • 35 years ~ 50 years
  • Female
Study Interest
  • Cancer (Ovarian)
Open

PRevention Of Frailty with Fisetin (PROFFi) in Breast Cancer Survivors

Are you a breast cancer survivor? if soy you may be eligible to participate in this research study that is looking at the effectiveness of fisetin and/or exercise on physical function assessed using a 6 minute walking distance in chemotherapy-treated postmenopausal breast cancer survivors

Age & Gender
  • 18 years ~ 70 years
  • Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Not currently enrolling

Metastatic Non-small Cell Lung Cancer Treatment

In this study, we want to see how patients with metastatic non-small cell lung cancer do with two treatments: ivonescimab and chemotherapy. We are comparing these treatments to find out which one helps patients more.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Open

EFFICACY AND SAFETY OF DIVARASIB VERSUS SOTORASIB OR ADAGRASIB IN PATIENTS WITH NON-SMALL CELL LUNG CANCER

Do you have non small cell lung cancer? Are you currently not on any other treatments for your cancer? If you answered yes, you may be able to take part in a lung cancer medication study.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
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