Have you been diagnosed with High-risk Biochemical Recurrence (BCR) of Nonmetastatic Castration-sensitive Prostate Cancer (nmCSPC)? If so, you may be able to take part in a research study evaluating the safety and tolerability of the study drug in adults with High-risk Biochemical Recurrence (BCR) of Nonmetastatic Castratio-sensitive Prostate Cancer (nmCSPC).

Do you have early-stage endometrial cancer? If so, you may be able to take part in a research study looking to find out if there are types of early-stage endometrial cancer that require less treatment than the usual approac

The purpose of this study is to understand how much people know about skin cancer and how they protect their skin. We are looking at people's knowledge about different types of skin cancer and their behaviors to prevent it. We want to see if there are common habits or barriers that affect how people take care of their skin. By learning more about these things, we hope to improve ways to promote skin health and prevent skin cancer.

Do you want to try out a smart ring? Do you want to get access to smartphone application which provides insightful information about your overall health, sleep, and activity? If you are between 40-59 years old, you may be able to participate in a research study assessing the feasibility and acceptability of Oura Rings.

Do you struggle with ways to feel more relaxed or calm when you are stressed? Do you identify as African American, Black, Hispanic, and/or Latino (a/e/x)? If so, you may be able to take part in a study to see whether a home-based training program can improve emotional well-being and heart health. Compensation provided.

Do you have advanced melanoma that has progressed on treatment? Do you have a tumor longer than 1cm in length? If so, you might be able to take part in a study that compares a study treatment (Vusolimogene Oderparepvec and Nivolumab) with your physician's choice of standard of care treatment. Compensation provided.

Have you been diagnosed with hormone receptor (HR+) and human epidermal growth factor receptor 2 (HER2)-negative recurrent or metastatic breast cancer? If so, you may be eligible for a clinical trial investigating the combination of endocrine therapy with alisertib.

Do you have moderate Parkinson's disease with motor symptoms? Are you over 45 years old? You may be able to participate in a research study to find out if a new treatment involving surgery can help with your symptoms. Compensation provided.

Have you been diagnosed with cancer. If so, you may be able to take part in a research study looking to improve cancer care for patients whose treatment outcomes have led to challenges in their quality of life.

The purpose of this research study is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on mucociliary clearance (MCC) - a test that shows the rate at which a person's lungs can clear inhaled particles. We will compare the rate of MCC at baseline (before treatment with HS), with MCC after a single dose of HS (acute treatment), and with MCC after two weeks of treatment with HS twice a day after 12 hours from the last dose of HS (sustained effect). We will also assess response to HS with other outcomes (lung function testing, changes in phlegm/mucus, and survey responses). If we find there is a sustained effect of HS, this would support the use of HS as part of airway clearance for people with bronchiectasis.