to evaluate the efficacy and safety of T-DXd in combination with bevacizumab versus bevacizumab monotherapy as first-line maintenance therapy, in participants with human epidermal growth factor 2 (HER2)-expressing (immunohistochemistry [IHC] 3+/2+/1+) advanced high-grade epithelial ovarian cancer.

Do you have type 2 diabetes with an A1c that is higher than what your doctor would like it to be? Do you have excess body weight that you would like to lose? If so, you may be eligible to participate in a research study to evaluate the effects of a new combination of medications.

Do you or your child have alopecia areata? Would you be interested in hearing more about a clinical study on alopecia areata? If so, you may be able to participate in a research study to find out how effective and safe the study medication ritlecitinib is in patients with alopecia areata.

Preventing walking disability in our rapidly aging population is an enormous public health challenge. Fundamental to their loss of functional mobility is that the muscles needed to power walking experience decline in function with age. Wearable assistive devices can be designed to augment the function of these muscles and may make walking easier. If you are a healthy older adult, you may be able to participate in a training intervention to determine the feasibility of a passive wearable ankle device that strengthens walking dynamics and decreases fall risk.

The purpose of this study is to determine the efficacy and safety of an investigational oral medication compared with placebo in people with obesity or overweight with and without type 2 diabetes

Are you living with chronic limb-threatening ischemia? You may be dealing with ongoing pain, hard-to-heal wounds, or tough choices about surgeries and treatments to save your leg or foot. We want to hear your story. What has it been like trying to get the care you need? Have you ever felt confused about your treatment options or wished for more support along the way? By sharing your experience, you can help us understand how to improve care for others facing the same condition. Maybe it's helping doctors explain things more clearly, finding better ways to manage pain, or offering support for people worried about losing their independence. We'll talk with you twice-once now and again in six months-to learn about your full journey, the highs and lows, and what really helped. Your voice can lead to real changes that make care better and less stressful for people in the future.

Are you curious about how social media affects child development? You and your child could participate in an exciting research study at UNC Chapel Hill! Compensation provided.

The purpose of this study is to explore the safety and efficacy of a study drug called Telisotuzumab adizutecan (ABBV-400) in combination with existing therapies in Metastatic Colorectal Cancer (mCRC) patients.

Looking for school staff, parents, and recent high school graduates to participate in a research study to learn more about how to help students feel more connected at school. Compensation provided.

The purpose is to examine the psychological processes underlying reading (and language comprehension more generally) in healthy, literate adults, focusing particularly on how the representation of information in memory supports and constrains processing. This will contribute to a greater understanding of the basic processes involved in reading, which may lead to improvements in education and more effective uses of information technology.