Have you recently been diagnosed with breast cancer but have not yet started treatment (other than surgery)? You may be able to take part in the UNC CogMAP study. In this study, we want to learn more about cognitive and brain function before and after cancer treatment. This will help us to better understand risk factors for experiencing cognitive difficulties during and after treatment.

Fuel for Thought: How do sugar and fat affect each other in the brain? Do you ever wonder what happens in your brain when you eat dessert? And why sugary and fatty foods are so appealing? If so, you may eligible to participate in a research study to understand the impact of sugar and fat on the brain!

If you are healthy and between the ages of 18-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

During puberty, adolescents grow and change a lot which may make life seem more stressful and emotional. Male and female adolescents experience the changes associated with puberty differently, possibly because of different responses to changes in hormones, including testosterone and estrogen. We are interested in learning more about the role of these hormones in regulating emotional processing and mood symptoms, and whether a mobile training program can help improve mood during the pubertal transition. Participation is 8 weeks with two monthly follow-up surveys. Compensation provided.

In this study, we want to learn more about the experiences and activities of high school-aged youth after a neurological event. This study will also help us to understand the perspectives of youth and a parent/caregiver through photos and stories.

We want to learn more about how executive functioning differs between children with ADHD, ASD, or neither. We have finished recruiting for our ADHD and typically developing groups but are still recruiting autistic children to be a part of our study. Children will complete an iPad-based measure of executive functioning and complete various tasks while their brain activity is being monitored using EEG. We will also complete a short eye-tracking task. Parents will fill out different forms to get an understanding of each child's developmental history and current behaviors.

If you or your child had or currently have abnormal cell growth or a related condition, including brain and nervous system tumors, you may be able to take part in a research study. This is a study for patients who are receiving treatment at UNC hospitals. In this study, we will collect samples to better understand the causes of your disease.

This is a survey study to help us learn more about how high schoolers engage in life activities after an unexpected health event. The results of the study will be used to inform healthcare providers and educators so they can help teenagers do things they want to after these health events.

The purpose of this research study is to see if adding the PARP inhibitor olaparib concurrently with SRS followed by immunotherapy (durvalumab) and chemotherapy will lead to better control of breast cancer that has spread to the brain better than the standard approach.

During pregnancy, birthing people are at greater risk of experiencing depression and irritable mood. The goal of the BUMP Study is to learn more about how pregnancy hormones relate to irritability and brain activity.