Are you living with obesity? Will you be willing to lose 25% of your body weight? You may be able to participate in a study to see if an investigational medication works better than placebo for weight loss. Eligible participants may also be able to enroll in an extension phase after the main study is done, where they will be guaranteed to receive the investigational medication.

Are you a young adult who drinks and uses social media? We are holding in-person workshops in downtown Chapel Hill to gather feedback from young adults who drink and use social media. Compensation provided.

Do you have plaque type psoriasis? You may be able to participate in a research study to find out if an investigational medication (zasocitinib) works better than an already FDA approved medication for psoriasis (deucravacitinib).

Are you currently using insulin to treat type 2 diabetes? Are your blood sugar values still not where your provider wants them to be? If you are willing to use an automated insulin delivery system, involving an insulin pump and a continuous glucose monitor, you may be eligible to participate in a research study to find out if the twiist system can improve glycemic control.

Do you have type 2 diabetes with an A1c that is higher than what your doctor would like it to be? Do you have excess body weight that you would like to lose? If so, you may be eligible to participate in a research study to evaluate the effects of a new combination of medications.

Do you or your child have alopecia areata? Would you be interested in hearing more about a clinical study on alopecia areata? If so, you may be able to participate in a research study to find out how effective and safe the study medication ritlecitinib is in patients with alopecia areata.

Are you curious about how social media affects child development? You and your child could participate in an exciting research study at UNC Chapel Hill! Compensation provided.

Are you living with chronic limb-threatening ischemia? You may be dealing with ongoing pain, hard-to-heal wounds, or tough choices about surgeries and treatments to save your leg or foot. We want to hear your story. What has it been like trying to get the care you need? Have you ever felt confused about your treatment options or wished for more support along the way? By sharing your experience, you can help us understand how to improve care for others facing the same condition. Maybe it's helping doctors explain things more clearly, finding better ways to manage pain, or offering support for people worried about losing their independence. We'll talk with you twice-once now and again in six months-to learn about your full journey, the highs and lows, and what really helped. Your voice can lead to real changes that make care better and less stressful for people in the future.

Looking for school staff, parents, and recent high school graduates to participate in a research study to learn more about how to help students feel more connected at school. Compensation provided.

Do you have type 1 diabetes? Has your doctor told you that your HbA1c is higher than the goal? Do you also have excess body weight? If you are having a hard time controlling your blood sugar with only insulin, you may be able to participate in a research study to see if taking an investigational medication once weekly can help improve your blood sugar control and reduce your body weight.