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387 studies match your search
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Pediatric Ravulizumab Study

This is a research study for pediatric patients previously been diagnosed with generalized myasthenia gravis (gMG) which is a condition that causes abnormalities of your immune system which may lead to generalized muscle weakness. This study looks at an investigational drug called ravulizumab (referred to as "study drug") to treat gMG by blocking complement activity that fights against infections. Although ravulizumab is approved to treat gMG in adults, in this study, ravulizumab is considered an experimental drug, which means it is not approved for use in treating children with gMG in any country at this time.

Age & Gender
  • 6 years ~ 17 years
  • Male, Female, Gender Inclusive
Study Interest
  • Bones, Joints, Muscles
  • Chronic Conditions
Open

Liver Cancer Screening Study

If you have liver cirrhosis or chronic hepatitis B infection, you may qualify to participate in a research study that compares the effectiveness of two liver cancer screening methods. Please contact the study team to get more information. Compensation provided.

Age & Gender
  • 18 years ~ 85 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Open

PRevention Of Frailty with Fisetin (PROFFi) in Breast Cancer Survivors

Are you a breast cancer survivor? if soy you may be eligible to participate in this research study that is looking at the effectiveness of fisetin and/or exercise on physical function assessed using a 6 minute walking distance in chemotherapy-treated postmenopausal breast cancer survivors

Age & Gender
  • 18 years ~ 70 years
  • Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Open

An Open-Label, Multicenter, First-in-Human, Dose-Escalation, Multicohort, Phase 1/2 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

Do you have With Locally Advanced or Metastatic Solid Tumors of the Head or Neck? If so, you may be able to participate in a research study to to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of INBRX 106 administered as a single agent or in combination with the anti-PD-1 checkpoint inhibitor (CPI) pembrolizumab (Keytruda®).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)
Open

Immune Functioning and Social Reward Processing in Autism and Typical Development

Are you interested in learning more about how the body and brain influences social behavior? If you are between 18 and 29 years old, you may be eligible to participate in our new EEG study! This project uses EEG and blood assaying techniques to understand how differences in immune functioning relates to the way that reward is processed in the brain. Compensation is provided.

Age & Gender
  • 18 years ~ 29 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Immune System/Infections
  • UNC or UNC Health employees
  • and 3 more
Open

Hydrolyzed Formula in Infants and Children with Cow's Milk Allergy

The purpose of this study is to determine if an extensively broken-down milk protein formula is safe for children with cow's milk protein allergy.

Age & Gender
  • 3 months ~ 12 years
  • Male, Female, Gender Inclusive
Study Interest
  • Allergy
Open

The effects of ankle push-off assistance on gait capacity

Preventing walking disability in our rapidly aging population is an enormous public health challenge. Fundamental to their loss of functional mobility is that the muscles needed to power walking experience disproportionate declines in function with age. Wearable assistive devices can be designed to augment the function of these muscles and may make walking easier. If you are a healthy young adult, you may be eligible to participate in a study to help guide the development of more effective exoskeleton designs!

Age & Gender
  • 18 years ~ 35 years
  • Male, Female, Gender Inclusive
Study Interest
  • Bones, Joints, Muscles
  • Healthy Volunteer or General Population
  • Movement
Open

EFFICACY AND SAFETY OF DIVARASIB VERSUS SOTORASIB OR ADAGRASIB IN PATIENTS WITH NON-SMALL CELL LUNG CANCER

Do you have non small cell lung cancer? Are you currently not on any other treatments for your cancer? If you answered yes, you may be able to take part in a lung cancer medication study.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Open

Age-related walking and balance control during 30-minute walking

Do we feel fear to fall when walking for a long period of time as we age? If you are a healthy older adult (65-99 yrs), you may be able to participate in a study to find out how aging affects neuromuscular control and postural control during prolonged walking and whether carbon fiber insoles can reduce muscle fatigue.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Bones, Joints, Muscles
  • Heart and Circulation
  • Healthy Volunteer or General Population
Open

Neutrophil Blood Cell Count Study

Are you Black/African American or have Middle Eastern ancestry? Are you not taking any medicines that could change your blood count? If so, you might be able to join a study to find out the normal levels of a type of blood cell called neutrophils. Compensation provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
  • UNC or UNC Health employees
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