NEU-411 is being studied to see if it can slow PD progression in individuals with PD who have LRRK2 pathway overactivity (referred to as LRRK2-driven) based on their genetic profile.

The purpose of this research study is to evaluate the safety and efficacy of pramipexole extended release (ER) versus escitalopram for the treatment of major depressive disorder (MDD) and mild neurocognitive disorder (MND) in people living with HIV (PWH). This study will also look at whether you experience any side effects from the study drugs.

This study aims to understand the challenges of using music therapy to support patients before and after surgery. While past research shows that music therapy can help reduce anxiety and the need for pain medications, it is not commonly used in hospitals. To explore this, researchers will interview surgeons, nurses, hospital staff, and patients to learn more about the barriers and how music therapy might be better included in surgical care.

to assess the attitude toward a newly adopted mortality and morbidity conference amongst surgical trainees

In this research study, we want to learn more about using DNA sequencing for individuals with severe mental illness. This may give clues about health risks now and in the future. You are being asked to participate in this research study because DNA sequencing may improve our understanding of schizophrenia, and what may be causing the type of illness that you have.

We are attempting to study social and political attitudes in the contemporary political context.

The primary endpoint for this study is subjects achieving either a decrease in Urgency Numeric Rating Scale (NRS) score of ≥ 2 points, or a decrease in score of ≥ 30%, at 12 weeks. Success is defined as ≥ 50% of enrolled subjects meeting the primary endpoint.

We are interested in finding ways to make political conversations go more smoothly. We will examine which conversations lead people to have more positive views of those they disagree with.

This study aims to estimate the national-level prevalence of workplace violence against healthcare workers in Nepal and explore associated factors

Determine the effectiveness of real-time CGM at reducing neonatal morbidity and mortality in pregnant individuals with T2DM, compared to regular blood sugar testing methods.