The research team from the Carolina Global Breastfeeding Institute is conducting a study on the implementation of IYCF-E in Western North Carolina (WNC) after Hurricane Helene. This research aims to share lessons learned and improve the quality of future relief efforts through: 1) sharing lived experiences; 2) assessing effectiveness of training; and 3) informing the state- and national-level policy recommendations for incorporating Infant and Young Child Feeding in Emergencies (IYCF-E) evidence-based practices.
To compare the prevalence, severity, and timing of chronic health conditions (CHC) in a cohort of patients with DS-AL (Down Syndrome Acute Leukemia) with age-comparable DS individuals that have no cancer history. Our secondary objectives will compare NP (Neuro-Psychological) and health-related quality of life outcomes in survivors of DS-AL compared with age-comparable DS individuals with no cancer history, and will identify risk determinants of CHC and NP late effects among survivors of DS-AL.
Hunter Syndrome or Mucopolysaccharidosis II (MPS II) is a rare genetic disorder caused by decreased levels of a specific enzyme, iduronate-2-sulfatase. Lack of this enzyme causes buildup of large sugar molecules called glycosaminoglycans (GAGs). The build up of GAGs causes significant damage to the body and brain. This extension study is evaluating the long-term safety and efficacy of JR-141, an enzyme replacement therapy, to provide the missing enzyme to the body. This allows for break down of the stored GAGs. JR-141 uses specific technology to cross the blood brain barrier so that the enzyme can get into the brain. JR-141 is expected to help both the cognitive (brain) and body effects of MPS II.
To explore people with lived and living experience (PWLLE) of opioid use and/or taking methadone on the feasibility of and interest in pharmacy-centered methadone access at rural community pharmacies. The model for which we will elicit PWLLE perspectives parallels several similar successful programs that exist outside of the US and several successful small-scale pilots that have been conducted in urban areas of the US, including NC.
This study aims to understand how adults who have completed a thru-hike of the Appalachian Trail planned for their thru-hike and adjusted their plans in response to different situations on the trail.
The purpose of this study is to learn more about the lining of the uterus, called the endometrium, by taking samples of endometrial tissue. Samples are taken by a common procedure called an endometrial biopsy. We will look at markers of inflammation and altered energy metabolism in people with and without endometriosis in order to better understand the disease and identify new and better ways to treat endometriosis.
The purpose of this study is to understand how employees interact with each other at work.
This study will ask parents who homeschool their high school-age children to provide information about how these students learn information literacy skills (specifically, how to find and evaluate sources). It seeks to better understand common information literacy practices and compare how information literacy is taught among different groups of homeschoolers in order to strengthen our understanding of how high schoolers encounter this important skill.
This study seeks to better understand food, nutrition and communication needs in Oceania to help create a needs assessment and information guide and/or recommendations. These resulting assessment and/or recommendation guides aim to help the region in addressing any needs or opportunities that arise, as it relates to topics such as food, nutrition, health and the environment/sustainability more broadly.
Exploring how artificial intelligence will affect the investment management landscape from a decision-making and company structure standpoint.