We are conducting two 3 hour in-person workshops with young adults who consume alcohol to support the development of an intervention which uses social medial to address the link between alcohol use and cancer risk.

Do you have plaque type psoriasis? You may be able to participate in a research study to find out if an investigational medication (zasocitinib) works better than an already FDA approved medication for psoriasis (deucravacitinib).

We are studying how well a new medicine called Sacituzumab Tirumotecan works by itself and when combined with another medicine called pembrolizumab. We are comparing these treatments to the usual chemotherapy to see which one is better and safer for people with a specific type of breast cancer that has come back or spread and can't be removed by surgery.

Have you diagnosed with lymph node positive early breast cancer, have received surgery, and have not received any systemic or radiation treatment prior to surgery? If so, you may be able to take part in this clinical trial which seeks to improve the treatment of early-stage breast cancer by examining ctDNA, a biomarker found in the blood that may indicate the presence of disease. This study aims to determine if ctDNA can help doctors personalize therapies leading to more effective treatment plans.

Do you have acid reflux, GERD, or Barrett's Esophagus? Are you having standard of care endoscopies performed? You may be able to participate in a research study testing for Barrett's Esophagus and esophageal cancer. Compensation provided.

Have you been diagnosed with Leukemia? Do you have a functioning kidney, liver, and cardiac organ? If so, you may be able to participate in a study on a new drug called LBS-007. We want to find out if it is safe for people with Leukemia. Compensation provided.

Spectra Discovery is a research study looking to see if wearable devices can measure screen time use in children ages 3 to 8. Your child will wear fake glasses and a shirt clip with light sensors to track light from screens. They will also wear an activity counter around their waist to track movement. During the study, your child will use a study-provided Android tablet, which includes an app to track screen use. The study lasts one week and includes: a baseline survey, daily time-use surveys, device logs at the end of each day, and a follow-up survey. To get started, parents will complete an online baseline survey and schedule an in-person orientation, either at home or at our Chapel Hill office. Families will be compensated for their time, and children will receive a thank-you gift. This study helps us learn if these wearable devices can measure screen use in young children.

Do you or your child have alopecia areata? Would you be interested in hearing more about a clinical study on alopecia areata? If so, you may be able to participate in a research study to find out how effective and safe the study medication ritlecitinib is in patients with alopecia areata.

Preventing walking disability in our rapidly aging population is an enormous public health challenge. Fundamental to their loss of functional mobility is that the muscles needed to power walking experience decline in function with age. Wearable assistive devices can be designed to augment the function of these muscles and may make walking easier. If you are a healthy older adult, you may be able to participate in a training intervention to determine the feasibility of a passive wearable ankle device that strengthens walking dynamics and decreases fall risk.

Most patients with generalized Myasthenia Gravis need treatments that carry substantial risk of side effects and toxicity, Descartes-08 is a cell therapy is a RNA based CAR-T that causes direct killing of target cells without serious generalized toxicities.