This study is being done to see how safe a study drug is and how well it will work to help people with type 2 diabetes mellitus (T2DM). We have asked you to join this study because you have T2DM. During this study, participants will come to the clinic and receive treatment for their T2DM. All patients will get study drug. During the study, the dosage of the study drug is increased to test the safety and effectiveness from higher doses.

Ever wonder how the way you walk may affect your knees? Have you ever had an ACL reconstruction? You may be able to take part in a study to learn more about how different types of force applied to your legs can affect your knee while walking on a treadmill.

The purpose of this research is to test the safety of NXC-201 (a CAR-T cell targeting the BCMA protein) at different doses in participants with relapsed/refractory AL amyloidosis, and to confirm the best dose for further testing. In addition, the study will evaluate the effectiveness of NXC-201 in treating relapsed/refractory AL amyloidosis

The main purpose of this study is to explore how aging affects not only the local organization of hippocampus but also the corresponding global connectivity. Additionally, the findings of age-dependent alteration on hippocampal subfield networks lay the foundation for the development of an early biomarker of Alzheimer's disease.

The purpose of this study is to determine if epcoritamab can be used to treat patients with previously treated WM.

The goal of this interview is to gather a clinician's perspective on the feasibility and potential integration of a new Geriatric Functional Assessment System (GFAS) into their clinical practice. This proposed system is a clinic-based wearable device designed to collect visual and motion data from older adults during their primary care visits that will help assess physical function. Its goal is to collect and process data, apply machine learning, and enable clinicians to identify early signs of functional decline.

This study aims to evaluate the effectand safety of empasiprubart compared with intravenous immunoglobulin (IVIg) treatment in adults with multifocal motor neuropathy (MMN). This study will also check how empasiprubart affects the body, how it is absorbed and removed from the body, and how the immune system reacts to empasiprubart.

Are you 21+ and regularly drink alcohol? You may be eligible for a study to help us learn what people think about alcohol. Participants who complete the study can earn up to $275 in virtual gift cards.

Do you have high blood pressure even though you are taking 3 or 4 different medications to treat it? You might be able to participate in a study to find out if you also have high cortisol levels.

The purpose of this study is to test the effectiveness and safety of the combination of an investigational vaccine, PDS0101, and the standard of care, compared to the standard of care treatment alone.