To see if taking a pill called Brepocitinib can help patients with cutaneous sarcoidosis

We are looking for adults ages 18-55 who are interested in using digital tools, a website, and text messages to help them make positive changes in their eating, activity, and weight.

Have you been diagnosed with advanced cancer that cannot be removed by surgery or has spread to a different part of the body (metastasis)? Has your disease has been getting worse on standard of care cancer treatment? If so, you may be able to take part in a research study looking at whether the experimental study drug, AI-081, is safe and well tolerated, and whether it is effective in treating advanced or metastatic cancer.

Test whether language processing effects can be seen in eye-movement analysis.

The purpose of this study is to determine whether a new investigational combination of drugs, that contains belantamab mafodotin with belantamab, will be as effective, and more tolerable, compared to belantamab mafodotin alone in participants with multiple myeloma that has become active again after at least three prior lines of treatment.

Are you in perimenopause? Are you interested in lifting weights and taking creatine supplements? Do you want to learn more about your body and brain? If so, you may be able to participate in a research study to understand the impact of resistance training and creatine on muscle quality and cognition in perimenopause!

This trial seeks to enroll patients diagnosed with HER2-negative (HER2- low or HER2-0)- MBC who are starting treatment with T-DXd. The purpose is to determine if the test used for HER2+ MBC also works for HER2-low MBC. By participating in this trial, you are contributing to information that may improve the care of future patients with HER2-negative (HER2- low or HER2-0)- MBC. This trial does not require additional biopsies. Only tissue left over from a standard-of-care procedure will be used. The study team will access your medical record to review routine imaging test results as well as track your response to your treatment. Your breast cancer care will be managed by your oncologist, and you won't need to interact with the study team for direct care. No extra visits with the study team are required, except possibly for the initial enrollment.

Are you planning on having an IUD placed? If you are already planning to get an IUD, this study gives the chance to receive extra pain medication during insertion. Everyone will receive standard pain medication, and 2/3 of volunteers will receive extra. We are looking to see if giving ketorolac pills 1-hour vs 2-hours before an IUD decreases pain levels. We would need 3 hours of in-person clinic time from volunteers. Compensation provided.

To determine the anti-proliferative effect of tirzepatide on the endometrium of endometrial cancer (EC) patients .

This study's findings will contribute to a broader understanding of how goal framing and self-regulatory tools can promote sustained engagement in health-related behaviors. Maintaining good health is essential for everyone. By participating in this study, you will help demonstrate the role of motivation in encouraging individuals to take action toward improving their health through health-related behaviors.