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2474 studies match your search
Not currently enrolling

Dose-escalation and expansion study of BAY 3375968 (anti-CCR8 antibody) as monotherapy and in combination with pembrolizumab in selected advanced solid tumors

This study will evaluate BAY 3375968 as a new immunotherapeutic agent in advanced solid tumor settings of high medical need.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder, Breast, Colorectal, and 5 more)
Open

The ARC Study

Help us advance research for cerebellum disorders! The ARC Study (Advancing Research for Cerebellum Disorders using 3T & 7T MRI) is currently looking for healthy participants to participate in a research study involving brain MRI scans. Participants can earn up to $100 in giftcards for participation.

Age & Gender
  • 14 years ~ 21 years
  • Female
Study Interest
  • Brain, Head, Nervous System
  • Developmental
  • Healthy Volunteer or General Population
  • UNC Students (undergrad, grad, professional)
Open

Pediatric Ravulizumab Study

This is a research study for pediatric patients previously been diagnosed with generalized myasthenia gravis (gMG) which is a condition that causes abnormalities of your immune system which may lead to generalized muscle weakness. This study looks at an investigational drug called ravulizumab (referred to as "study drug") to treat gMG by blocking complement activity that fights against infections. Although ravulizumab is approved to treat gMG in adults, in this study, ravulizumab is considered an experimental drug, which means it is not approved for use in treating children with gMG in any country at this time.

Age & Gender
  • 6 years ~ 17 years
  • Male, Female, Gender Inclusive
Study Interest
  • Bones, Joints, Muscles
  • Chronic Conditions

Dara-RVd Induction for newly diagnosed multiple myeloma with autologous stem cell transplantation

In this study, we want to see what happens when one of the drugs in a 4-drug combination called Dara-RVd is given once a week instead of twice a week. We will look at how this timing change affects the outcome of multiple myeloma with autologous stem cell transplantation. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Multiple Myeloma)
Open

Liver Cancer Screening Study

If you have liver cirrhosis or chronic hepatitis B infection, you may qualify to participate in a research study that compares the effectiveness of two liver cancer screening methods. Please contact the study team to get more information. Compensation provided.

Age & Gender
  • 18 years ~ 85 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Open

PRevention Of Frailty with Fisetin (PROFFi) in Breast Cancer Survivors

Are you a breast cancer survivor? if soy you may be eligible to participate in this research study that is looking at the effectiveness of fisetin and/or exercise on physical function assessed using a 6 minute walking distance in chemotherapy-treated postmenopausal breast cancer survivors

Age & Gender
  • 18 years ~ 70 years
  • Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Not currently enrolling

Akero 106

We are studying an investigational drug, Efruxifermin, to see if it will help in the treatment of liver inflammation and scarring (fibrosis) in adults diagnosed with Compensated Cirrhosis due to NASH (non-alcoholic steatohepatitis) and MASH (metabolic dysfunction-associated steatohepatitis).

Age & Gender
  • 18 years ~ 80 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Open

An Open-Label, Multicenter, First-in-Human, Dose-Escalation, Multicohort, Phase 1/2 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

Do you have With Locally Advanced or Metastatic Solid Tumors of the Head or Neck? If so, you may be able to participate in a research study to to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of INBRX 106 administered as a single agent or in combination with the anti-PD-1 checkpoint inhibitor (CPI) pembrolizumab (Keytruda®).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)
Open

Immune Functioning and Social Reward Processing in Autism and Typical Development

Are you interested in learning more about how the body and brain influences social behavior? If you are between 18 and 29 years old, you may be eligible to participate in our new EEG study! This project uses EEG and blood assaying techniques to understand how differences in immune functioning relates to the way that reward is processed in the brain. Compensation is provided.

Age & Gender
  • 18 years ~ 29 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Immune System/Infections
  • UNC or UNC Health employees
  • and 3 more
Open

Hydrolyzed Formula in Infants and Children with Cow's Milk Allergy

The purpose of this study is to determine if an extensively broken-down milk protein formula is safe for children with cow's milk protein allergy.

Age & Gender
  • 3 months ~ 12 years
  • Male, Female, Gender Inclusive
Study Interest
  • Allergy
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