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2529 studies match your search
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ARGX-117-2302- Phase 3, Randomized, Double-Blind study to evaluate effectiveness and safety of empasiprubart versus IVIg in patients with multifocal motor neuropathy

This study aims to evaluate the effectand safety of empasiprubart compared with intravenous immunoglobulin (IVIg) treatment in adults with multifocal motor neuropathy (MMN). This study will also check how empasiprubart affects the body, how it is absorbed and removed from the body, and how the immune system reacts to empasiprubart.

Age & Gender
  • 18 years ~ 99 years
  • Male, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Not currently enrolling

Geriatric Functional Assessment System: A Clinician's Perspective

The goal of this interview is to gather a clinician's perspective on the feasibility and potential integration of a new Geriatric Functional Assessment System (GFAS) into their clinical practice. This proposed system is a clinic-based wearable device designed to collect visual and motion data from older adults during their primary care visits that will help assess physical function. Its goal is to collect and process data, apply machine learning, and enable clinicians to identify early signs of functional decline.

Age & Gender
  • 22 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Injury/Injury Prevention
  • Opinions and Perceptions
  • UNC or UNC Health employees
Visit Location
100% Remote (online, phone, text)

Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/​Metastatic Head and Neck Squamous Cell Carcinoma

The purpose of this study is to test the effectiveness and safety of the combination of an investigational vaccine, PDS0101, and the standard of care, compared to the standard of care treatment alone.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)
Open

Alcohol Labeling Study

Are you 21+ and regularly drink alcohol? You may be eligible for a study to help us learn what people think about alcohol. Participants who complete the study can earn up to $275 in virtual gift cards.

Age & Gender
  • 21 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
Open

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

Have you been diagnosed with advanced cancer that cannot be removed by surgery or has spread to a different part of the body (metastasis)? Has your disease has been getting worse on standard of care cancer treatment? If so, you may be able to take part in a research study looking at whether the experimental study drug, AI-081, is safe and well tolerated, and whether it is effective in treating advanced or metastatic cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
Not currently enrolling

Text Messaging Weight Loss Program for Adults

We are looking for adults ages 18-55 who are interested in using digital tools, a website, and text messages to help them make positive changes in their eating, activity, and weight.

Age & Gender
  • 18 years ~ 55 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Healthy Volunteer or General Population
  • Obesity
  • Movement
Visit Location
Not currently enrolling

Where do you look when you listen to stories?

Test whether language processing effects can be seen in eye-movement analysis.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
  • UNC Students (undergrad, grad, professional)
Coming Soon

Safety and Efficacy of Belantamab Monotherapy and in Combination Treatments for the Treatment of Multiple Myeloma

The purpose of this study is to determine whether a new investigational combination of drugs, that contains belantamab mafodotin with belantamab, will be as effective, and more tolerable, compared to belantamab mafodotin alone in participants with multiple myeloma that has become active again after at least three prior lines of treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Multiple Myeloma)
Open

C4391024: "AN INTERVENTIONAL, OPEN-LABEL, RANDOMIZED, MULTICENTER PHASE 3 STUDY OF PF-07220060 PLUS LETROZOLE COMPARED TO CDK4/6 INHIBITOR PLUS LETROZOLE IN PARTICIPANTS OVER 18 YEARS OF AGE WITH HORMONE RECEPTOR (HR)-POSITIVE, HER2-NEGATIVE ADVANCED/METASTATIC BREAST CANCER WHO HAVE NOT RECEIVED ANY PRIOR SYSTEMIC ANTICANCER TREATMENT FOR ADVANCED/METASTATIC DISEASE (FOURLIGHT-3)"

Have you been diagnosed hormone receptor (HR) positive, human epidermal growth factor receptor 2 (HER2) negative, locally advanced or metastatic breast cancer, and have not received any systemic anti-cancer treatment for the disease. The study will explore the effects of the study drug PF-07220060 plus letrozole and if it is more effective compared to currently approved drugs (palbociclib, abemaciclib, or ribociclib) in combination with letrozole. This study is different from your regular medical care. The purpose of your regular medical care is to manage or improve your health, but the purpose of research is to gather information to advance science and medicine and does not replace your regular medical care.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Breast)
Open

Ketorolac for IUD Pain Control

Are you planning on having an IUD placed? If you are already planning to get an IUD, this study gives the chance to receive extra pain medication during insertion. Everyone will receive standard pain medication, and 2/3 of volunteers will receive extra. We are looking to see if giving ketorolac pills 1-hour vs 2-hours before an IUD decreases pain levels. We would need 3 hours of in-person clinic time from volunteers. Compensation provided.

Age & Gender
  • 18 years ~ 99 years
  • Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
  • Sexual and/or Reproductive Health
  • Wellness and Lifestyle
  • Women's Health
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