Do you have plaque type psoriasis? You may be able to participate in a research study to find out if an investigational medication (zasocitinib) works better than an already FDA approved medication for psoriasis (deucravacitinib).

This study is being done to see if an investigational medication works better than a placebo (dummy medicine) for weight loss.

Are you a young adult who drinks and uses social media? We are holding in-person workshops in downtown Chapel Hill to gather feedback from young adults who drink and use social media. Compensation provided.

The purpose of this study is to collect cells from your esophagus using a special tool called the EndoSign® Cell Collection Device and test them to check for a condition called Barrett's Esophagus and esophageal cancer (EAC).

This research study seeks to improve the treatment of early-stage breast cancer by examining circulating tumor DNA (ctDNA). CtDNA, a biomarker found in the blood, may indicate the presence of residual disease after initial treatment. The study aims to determine if ctDNA analysis can help doctors personalize adjuvant therapies, such as radiation and systemic therapy, leading to more effective treatment plans. A significant focus is placed on including African American/Black patients, a population often underrepresented in genomic research. By analyzing ctDNA in this group, researchers hope to gain valuable insights into the disease's characteristics and improve treatment outcomes, ultimately reducing disparities in breast cancer care. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.

In this study, we want to see if a new drug called LBS-007 can help treat or cure leukemia. We want to find out if it is safe and if it works well for people with this disease.

Are you currently using insulin to treat type 2 diabetes? Are your blood sugar values still not where your provider wants them to be? If you are willing to use an automated insulin delivery system, involving an insulin pump and a continuous glucose monitor, you may be eligible to participate in a research study to find out if the twiist system can improve glycemic control.

Do you have type 2 diabetes with an A1c that is higher than what your doctor would like it to be? Do you have excess body weight that you would like to lose? If so, you may be eligible to participate in a research study to evaluate the effects of a new combination of medications.

Do you or your child have alopecia areata? Would you be interested in hearing more about a clinical study on alopecia areata? If so, you may be able to participate in a research study to find out how effective and safe the study medication ritlecitinib is in patients with alopecia areata.

Are you curious about how social media affects child development? You and your child could participate in an exciting research study at UNC Chapel Hill! Compensation provided.